High content imaging-based assay to classify estrogen receptor-α ligands based on defined mechanistic outcomes.
about
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activationHigh throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulatorFeed-forward inhibition of androgen receptor activity by glucocorticoid action in human adipocytes.Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays.Differential Regulation of Progesterone Receptor-Mediated Transcription by CDK2 and DNA-PKCoactivators enable glucocorticoid receptor recruitment to fine-tune estrogen receptor transcriptional responses.Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-α protein levels and activity.Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assaysInhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancerCharacterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis.Use of HCA in subproteome-immunization and screening of hybridoma supernatants to define distinct antibody binding patterns.The myImageAnalysis project: a web-based application for high-content screening.
P2860
Q24294591-8B2340FE-A9EB-4CF0-A56E-60D2AD1AB542Q28830542-A95FCEB3-1144-44F9-8C25-150AC8D3E9DEQ34657242-93A395AB-8DE6-4D1F-986F-8433FA4969B5Q34993998-677A6356-C503-476F-A6F4-73CD490B34EFQ36688106-CB6DDC94-5485-4E6B-979D-D7DB0E489A35Q36769499-A42F77AC-1CC6-4A67-992D-D98D02BCE064Q36912137-6323DF2A-6C73-43FE-92A8-47FC926BA72DQ36936203-2F72EF70-E852-4C29-8F29-3F895BA51DC9Q37240152-87333DB2-6314-4579-AE48-7F5454F102DDQ38697446-700F425D-5998-42CB-B1FB-5F1134B99C21Q41935072-491463A6-82CE-4B03-A089-31CE7B623C18Q41977956-2705A615-961A-43E1-8BCD-6EADC1B309F0
P2860
High content imaging-based assay to classify estrogen receptor-α ligands based on defined mechanistic outcomes.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
High content imaging-based ass ...... defined mechanistic outcomes.
@ast
High content imaging-based ass ...... defined mechanistic outcomes.
@en
type
label
High content imaging-based ass ...... defined mechanistic outcomes.
@ast
High content imaging-based ass ...... defined mechanistic outcomes.
@en
prefLabel
High content imaging-based ass ...... defined mechanistic outcomes.
@ast
High content imaging-based ass ...... defined mechanistic outcomes.
@en
P2093
P2860
P1433
P1476
High content imaging-based ass ...... defined mechanistic outcomes.
@en
P2093
F J Ashcroft
J Y Newberg
M A Mancini
P2860
P356
10.1016/J.GENE.2011.01.009
P407
P577
2011-01-20T00:00:00Z