A biosensor generated via high-throughput screening quantifies cell edge Src dynamics - Wikidata - awgldk - TriplyDB

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

http://www.wikidata.org/entity/Q30502428

about

Intracellular targeting with engineered proteins Current approaches to studying membrane organization A novel 3D fibril force assay implicates src in tumor cell force generation in collagen networks Structural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein libraries Nanobodies and recombinant binders in cell biology Spatiotemporal regulation of Src and its substrates at invadosomes Conversion of a Single Polypharmacological Agent into Selective Bivalent Inhibitors of Intracellular Kinase Activity Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase.Isolation of monobodies that bind specifically to the SH3 domain of the Fyn tyrosine protein kinase.PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility.Automated line scan analysis to quantify biosensor activity at the cell edge Subcellular and Dynamic Coordination between Src Activity and Cell Protrusion in Microenvironment Ratiometric Imaging Using a Single Dye Enables Simultaneous Visualization of Rac1 and Cdc42 Activation.Anchored design of protein-protein interfaces.Converting a binding protein into a biosensing conformational switch using protein fragment exchange.Knowledge-based design of a biosensor to quantify localized ERK activation in living cells.Detection of biomarkers using recombinant antibodies coupled to nanostructured platforms Design Principles for SuCESsFul Biosensors: Specific Fluorophore/Analyte Binding and Minimization of Fluorophore/Scaffold Interactions Environment-sensing merocyanine dyes for live cell imaging applications Live-cell fluorescence microscopy with molecular biosensors: what are we really measuring?Beyond Antibodies as Binding Partners: The Role of Antibody Mimetics in Bioanalysis.Imaging the coordination of multiple signalling activities in living cells.Monitoring of post-translational modification dynamics with genetically encoded fluorescent reporters Fluorescent Reporters and Biosensors for Probing the Dynamic Behavior of Protein Kinases Characterization of monobody scaffold interactions with ligand via force spectroscopy and steered molecular dynamics.Equilibrium and dynamic design principles for binding molecules engineered for reagentless biosensors.Directed Evolution to Engineer Monobody for FRET Biosensor Assembly and Imaging at Live-Cell Surface.

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A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

http://www.wikidata.org/entity/Q30502428

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

@ast

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

@en

type

label

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

@ast

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

@en

prefLabel

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

@ast

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

@en

P1433

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P1433

Nature Chemical Biology

P1476

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

@en

P2093

Brian Dewar

http://www.w3.org/2001/XMLSchema#string

Brian K Kay

http://www.w3.org/2001/XMLSchema#string

Brian Kuhlman

http://www.w3.org/2001/XMLSchema#string

Dmitriy Gremyachinskiy

http://www.w3.org/2001/XMLSchema#string

Jianrong Wu

http://www.w3.org/2001/XMLSchema#string

Klaus M Hahn

http://www.w3.org/2001/XMLSchema#string

Lee M Graves

http://www.w3.org/2001/XMLSchema#string

Richard Allen

http://www.w3.org/2001/XMLSchema#string

Steven Lewis

http://www.w3.org/2001/XMLSchema#string

Tim Elston

http://www.w3.org/2001/XMLSchema#string

P2860

Localized Rac activation dynamics visualized in living cells

Functions of the adapter protein Cas: signal convergence and the determination of cellular responses

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

Activation of endogenous Cdc42 visualized in living cells

Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein

Probing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor.

The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements

Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

An improved cyan fluorescent protein variant useful for FRET

P2888

P304

437-444

http://www.w3.org/2001/XMLSchema#string

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scholarly article

P356

10.1038/NCHEMBIO.585

http://www.w3.org/2001/XMLSchema#string

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P50

P577

2011-06-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51212985

http://www.w3.org/2001/XMLSchema#string

P698

21666688

http://www.w3.org/2001/XMLSchema#string

P921

High-throughput screening

biosensing technique

P932

3135387

http://www.w3.org/2001/XMLSchema#string