The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements
about
Src kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophilsRho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular traffickingBeta2-adaptin binds actopaxin and regulates cell spreading, migration and matrix degradationMicrotubule and Actin Interplay Drive Intracellular c-Src TraffickingThe spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imagingActin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary glandTRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-betaCritical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signallingBlockade of fatty acid synthase triggers significant apoptosis in mantle cell lymphomaEngineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms.Role of Src homology domain binding in signaling complexes assembled by the murid γ-herpesvirus M2 protein.Targeting protein lipidation in diseaseVisualization of Src activity at different compartments of the plasma membrane by FRET imaging.Regulation of cell death by recycling endosomes and golgi membrane dynamics via a pathway involving Src-family kinases, Cdc42 and Rab11a.Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions.A biosensor generated via high-throughput screening quantifies cell edge Src dynamicsPremature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn.Dissecting motility signaling through activation of specific Src-effector complexesInteraction between src family kinases and rho-kinase in agonist-induced Ca2+-sensitization of rat pulmonary artery.Germ cell transport across the seminiferous epithelium during spermatogenesis.DHHC20: a human palmitoyl acyltransferase that causes cellular transformationC-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.c-Src drives intestinal regeneration and transformation.RhoB differentially controls Akt function in tumor cells and stromal endothelial cells during breast tumorigenesisPTPepsilon has a critical role in signaling transduction pathways and phosphoprotein network topology in red cells.The intracellular dynamic of protein palmitoylationIdentification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screeningNa/K-ATPase mimetic pNaKtide peptide inhibits the growth of human cancer cells.Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation.Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransductionc-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood-testis barrier axis via its effects on protein recruitment and distribution.The mechanisms and significance of up-regulation of RhoB expression by hypoxia and glucocorticoid in rat lung and A549 cells.Src-mediated caveolin-1 phosphorylation affects the targeting of active Src to specific membrane sites.The residue at position 5 of the N-terminal region of Src and Fyn modulates their myristoylation, palmitoylation, and membrane interactions.A model for phospho-caveolin-1-driven turnover of focal adhesions.Endosomal signaling and cell migration.Single-cell imaging of mechanotransduction in endothelial cells.Endocytosis and the Src family of non-receptor tyrosine kinasesUnderstanding Protein Palmitoylation: Biological Significance and EnzymologyFAK, talin and PIPKIγ regulate endocytosed integrin activation to polarize focal adhesion assembly.
P2860
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P2860
The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements
description
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im August 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/08/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/08/01)
@nl
наукова стаття, опублікована в серпні 2007
@uk
مقالة علمية (نشرت في أغسطس 2007)
@ar
name
The membrane targeting and spa ...... hoB/RhoD endosome requirements
@ast
The membrane targeting and spa ...... hoB/RhoD endosome requirements
@en
The membrane targeting and spa ...... hoB/RhoD endosome requirements
@nl
type
label
The membrane targeting and spa ...... hoB/RhoD endosome requirements
@ast
The membrane targeting and spa ...... hoB/RhoD endosome requirements
@en
The membrane targeting and spa ...... hoB/RhoD endosome requirements
@nl
prefLabel
The membrane targeting and spa ...... hoB/RhoD endosome requirements
@ast
The membrane targeting and spa ...... hoB/RhoD endosome requirements
@en
The membrane targeting and spa ...... hoB/RhoD endosome requirements
@nl
P921
P356
P1476
The membrane targeting and spa ...... hoB/RhoD endosome requirements
@en
P2093
Valerie G Brunton
P304
P356
10.1242/JCS.003657
P407
P577
2007-07-10T00:00:00Z