about
The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAMRecognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.PKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in NeuronsCyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP SynthaseStructure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAAParacoccus yeeii sp. nov. (formerly CDC group EO-2), a novel bacterial species associated with human infection.Host-cell sensors for Plasmodium activate innate immunity against liver-stage infectionAntiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphatesHuman T regulatory cells can use the perforin pathway to cause autologous target cell death.RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cellsA human in vitro whole blood assay to predict the systemic cytokine response to therapeutic oligonucleotides including siRNABinding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA.Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.Accumulation of ALDH1-positive cells after neoadjuvant chemotherapy predicts treatment resistance and prognosticates poor outcome in ovarian cancer.Plasmacytoid dendritic cells--virus experts of innate immunity.Development and function of murine B220+CD11c+NK1.1+ cells identify them as a subset of NK cellsPlasmacytoid dendritic cells: in search of their niche in immune responses.Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNABeyond double-stranded RNA-type I IFN induction by 3pRNA and other viral nucleic acids.RNA recognition via TLR7 and TLR8.Accessing the therapeutic potential of immunostimulatory nucleic acids.Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist.Approaching the RNA ligand for RIG-I?The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infectionsNucleic acid adjuvants: toward an educated vaccine.Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis.Translating nucleic acid-sensing pathways into therapies.cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites.Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice.A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.Targeted activation of RNA helicase retinoic acid-inducible gene-I induces proimmunogenic apoptosis of human ovarian cancer cells.Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.Higher activation of TLR9 in plasmacytoid dendritic cells by microbial DNA compared with self-DNA based on CpG-specific recognition of phosphodiester DNA.MDA-5 activation by cytoplasmic double-stranded RNA impairs endothelial function and aggravates atherosclerosis.Exonuclease TREX1 also Has a Sweet Tooth.Antigen persistence and time of T-cell tolerization determine the efficacy of tolerization protocols for prevention of skin graft rejection.RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids.Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation.Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo.Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing.
P50
Q24299577-87202080-0B64-45A2-9B1A-54D84430BAEFQ24310706-18260AFE-83AD-49E5-943F-98871CDDCA6FQ27473291-F60C6637-19C9-4EB3-BF96-BC6EC71437DEQ27678007-11CBBDBB-D6D2-4B4B-836B-336DCC53590AQ27679344-1FBB2393-499C-4D51-977C-33D0FF75AA8AQ30775048-CECCFF87-92EC-4885-97FF-36CC1F673113Q33896690-4006001C-3D9A-4A41-A968-18FCF34C28A6Q34362314-E029CA07-3DF3-4318-ACCE-25D041D82E78Q34551876-C0256E1D-F1DB-4BD5-9BDA-D6F8D07602A7Q34709924-43AD9905-8B1F-4960-84BB-24134CC9B78CQ34936725-9F015A63-9815-491D-8CA4-C58C710F63D8Q35238345-80BA7335-CC7C-49D3-A1CF-C108FC48F40AQ35239001-64C273D8-5183-4535-A4FB-3994929E409BQ36140826-479BE2DD-A795-4FD1-B903-D11411A1AB43Q36180235-C0640EAE-302C-4F0F-821D-E229E6B4B333Q36229116-D28B9E62-684D-464E-ABCF-DB943ED33C09Q36232671-69711892-C5D5-43EC-A038-CE992D4C0935Q36345491-FA43FE2C-7E1E-4716-B544-96AAE9661C46Q36985388-380803D2-DA5F-4F3B-9939-5E5400C0A08BQ37028825-124B95B5-5DCD-49BF-BAAC-B650BAECECF8Q37225978-7C14FF50-979D-412D-932B-11C9C0914CC4Q37254398-869E3CEC-0F7B-464C-8620-C1436F20D032Q37361445-694286AD-1C3E-495E-82F7-5430779DBE10Q37374119-0DA0785B-533D-4FBE-83D0-D65139C025B8Q37997193-8E8FDFA8-8B8D-4406-89D6-2AA651B9A99DQ38288045-6A1EDD39-7351-4C5C-B250-01B4164B0815Q38570333-EF26CF48-1922-4F07-9B42-7EA97132AB0CQ38741351-B3A13806-8876-4BC2-8494-EE25A42D8682Q38748161-55F873A1-BC7E-4238-B300-8688B51A85E7Q39439571-8974A629-D05D-4036-8BA6-43DC7FAC0833Q39692679-4371DAA8-5724-4D0E-8155-D7BA13357BF0Q39774272-BC6538F0-83D2-4C80-893E-54B17D6C6A85Q39822897-EEFF4D6D-15D7-49FD-8A6C-F5F23288509EQ40775187-AB16065F-240B-4B26-AECF-1AEFBA43243EQ40995800-D0E129F0-FB3F-4E66-A980-E5AF39AA199FQ41009448-908A0E91-A608-4824-B146-A8D904FBC028Q41360656-561E11C0-1239-47F9-96C8-8212120F436DQ41957299-7F22CC67-2B49-446D-AD16-502E6BC31FD2Q41996467-15FFB599-BBE4-4158-BC35-F2C0CD7740DAQ44535307-4BE342D4-E8CD-42A3-9192-9B4791A0D5DC
P50
description
hulumtues
@sq
researcher
@en
ricercatore
@it
wetenschapper
@nl
հետազոտող
@hy
name
Winfried Barchet
@ast
Winfried Barchet
@en
Winfried Barchet
@es
Winfried Barchet
@fr
Winfried Barchet
@nl
Winfried Barchet
@sl
type
label
Winfried Barchet
@ast
Winfried Barchet
@en
Winfried Barchet
@es
Winfried Barchet
@fr
Winfried Barchet
@nl
Winfried Barchet
@sl
prefLabel
Winfried Barchet
@ast
Winfried Barchet
@en
Winfried Barchet
@es
Winfried Barchet
@fr
Winfried Barchet
@nl
Winfried Barchet
@sl
P214
P106
P21
P214
P31
P496
0000-0002-6745-6606
P734
P735
P7859
viaf-187728269