Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA - Wikidata - awgldk - TriplyDB

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

http://www.wikidata.org/entity/Q36345491

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STING: infection, inflammation and cancer RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA DNA sensor cGAS-mediated immune recognition Cellular and molecular regulation of innate inflammatory responses Viral evasion of intracellular DNA and RNA sensing Nonspecific DNA Binding of cGAS N Terminus Promotes cGAS Activation.Friend or Foe: Innate Sensing of HIV in the Female Reproductive Tract.PKC-δ isoform plays a crucial role in Tat-TLR4 signalling pathway to activate NF-κB and CXCL8 production IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1.Cytoplasm-Translocated Ku70/80 Complex Sensing of HBV DNA Induces Hepatitis-Associated Chemokine Secretion.IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes.Human microglia and astrocytes express cGAS-STING viral sensing components.Advanced Design of Dumbbell-shaped Genetic Minimal Vectors Improves Non-coding and Coding RNA Expression.Viral evasion of DNA-stimulated innate immune responses.The role of cGAS in innate immunity and beyond.Discriminating self from non-self in nucleic acid sensing.Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling.Sequence-Specific Sensing of Nucleic Acids.Innate recognition of microbial-derived signals in immunity and inflammation.Crosstalk between Cytoplasmic RIG-I and STING Sensing Pathways.G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes.Cytosolic nucleic acid sensors and innate immune regulation.Immune Diseases Associated with TREX1 and STING Dysfunction.Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.Role of Innate Genes in HIV Replication.Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation.Length does matter for cGAS.cGAS is activated by DNA in a length-dependent manner.RIG-I-Like Receptors and Type I Interferonopathies.An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway.Reading the fine print: sequence-specific activation of cGAS.Lymphocytes eject interferogenic mitochondrial DNA webs in response to CpG and non-CpG oligodeoxynucleotides of class C.Endogenous Retrovirus 3 - History, Physiology, and Pathology.Cytosolic sensing of immuno-stimulatory DNA, the enemy within.cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.Activation of the Innate Immune Receptors: Guardians of the Micro Galaxy : Activation and Functions of the Innate Immune Receptors.Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria.Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes.

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Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

http://www.wikidata.org/entity/Q36345491

description

2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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name

Sequence-specific activation o ...... as found in primary HIV-1 cDNA

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Sequence-specific activation o ...... as found in primary HIV-1 cDNA

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Sequence-specific activation o ...... as found in primary HIV-1 cDNA

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Sequence-specific activation o ...... as found in primary HIV-1 cDNA

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Sequence-specific activation o ...... as found in primary HIV-1 cDNA

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Sequence-specific activation o ...... as found in primary HIV-1 cDNA

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Nature Immunology

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Sequence-specific activation o ...... as found in primary HIV-1 cDNA

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Anna-Maria Herzner

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Christina Mertens

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Christoph Coch

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Cristina Amparo Hagmann

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Damian Ackermann

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Janos Ludwig

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Liudmila Andreeva

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Marion Goldeck

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Sabine Wittmann

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Steven Wolter

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P2860

A Toll-like receptor recognizes bacterial DNA

IFI16 is an innate immune sensor for intracellular DNA

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

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1025-1033

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10.1038/NI.3267

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10

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16

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Karl-Peter Hopfner

Winfried Barchet

Gunther Hartmann

Kirsten Kübler

Thomas Zillinger

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2015-09-07T00:00:00Z

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26343537

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4669199

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