about
Switches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination systemWhen ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling.Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses.Competing to coordinate cell fate decisions: the MST2-Raf-1 signaling deviceThe ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.DYVIPAC: an integrated analysis and visualisation framework to probe multi-dimensional biological networks.Signalling by protein phosphatases and drug development: a systems-centred view.Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation.Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches.Hypoxia-inducible factor (HIF) network: insights from mathematical models.Feedback regulation in cell signalling: Lessons for cancer therapeutics.Understanding complexity in the HIF signaling pathway using systems biology and mathematical modeling.Relationship between serum response factor and androgen receptor in prostate cancer.Integrated signaling pathway and gene expression regulatory model to dissect dynamics of Escherichia coli challenged mammary epithelial cells.Species differential regulation of COX2 can be described by an NFκB-dependent logic AND gate.Polyubiquitin chain assembly and organization determine the dynamics of protein activation and degradation.Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling.Regulation of oscillation dynamics in biochemical systems with dual negative feedback loops.On the functional diversity of dynamical behaviour in genetic and metabolic feedback systems.A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.On multiple regulatory mechanisms in the tryptophan operon system in Escherichia coli: in silico study of perturbation dynamics.Dynamics of ubiquitin-mediated signalling: insights from mathematical modelling and experimental studies.MST2-RASSF protein-protein interactions through SARAH domains.Distinct noise-controlling roles of multiple negative feedback mechanisms in a prokaryotic operon system.Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer.Protein–protein interactions generate hidden feedback and feed-forward loops to trigger bistable switches, oscillations and biphasic dose–responsesA dynamic model of the hypoxia-inducible factor 1a (HIF-1a) networkUbiquitin chain specific auto-ubiquitination triggers sustained oscillation, bistable switches and excitable firingLC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagyCoupled feedback regulation of nuclear factor of activated T-cells (NFAT) modulates activation-induced cell death of T cells
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Lan K Nguyen
@en
Lan K Nguyen
@es
Lan K Nguyen
@nl
Lan K Nguyen
@sl
Lan Nguyen
@fr
type
label
Lan K Nguyen
@en
Lan K Nguyen
@es
Lan K Nguyen
@nl
Lan K Nguyen
@sl
Lan Nguyen
@fr
prefLabel
Lan K Nguyen
@en
Lan K Nguyen
@es
Lan K Nguyen
@nl
Lan K Nguyen
@sl
Lan Nguyen
@fr
P106
P21
P31
P496
0000-0003-4040-7705