A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
about
Systems biology of the microvasculatureA systems biology view of blood vessel growth and remodellingSubstrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling PathwaysREST is a hypoxia-responsive transcriptional repressorFoxO3a modulates hypoxia stress induced oxidative stress and apoptosis in cardiac microvascular endothelial cellsMetabolic requirements for the maintenance of self-renewing stem cells.Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses.Computational systems biology approaches to anti-angiogenic cancer therapeutics.The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.Role of compartmentalization on HiF-1α degradation dynamics during changing oxygen conditions: a computational approach.Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and CancerRole of hypoxia-related proteins in invasion of ameloblastoma cells: crosstalk between NOTCH1, hypoxia-inducible factor 1α, a disintegrin and metalloproteinase 12, and heparin-binding epidermal growth factor.Modeling the interplay between the HIF-1 and p53 pathways in hypoxiaModeling dioxygenase enzyme kinetics in familial paraganglioma.Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model.Secretome identification of immune cell factors mediating metastatic cell homing.Unveiling Hidden Dynamics of Hippo Signalling: A Systems Analysis.Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinoma.Hypoxia-inducible factor (HIF) network: insights from mathematical models.Hypoxia-sensitive pathways in inflammation-driven fibrosis.Clinical implications of hypoxia biomarker expression in head and neck squamous cell carcinoma: a systematic review.Understanding complexity in the HIF signaling pathway using systems biology and mathematical modeling.Genomic insights into ayurvedic and western approaches to personalized medicine.REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia.Tight control of hypoxia-inducible factor-α transient dynamics is essential for cell survival in hypoxia.Intestinal hypoxia and hypoxia-induced signalling as therapeutic targets for IBD.Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling. [corrected].A microfluidic oxygen gradient demonstrates differential activation of the hypoxia-regulated transcription factors HIF-1α and HIF-2α.Epithelial membrane protein 2 (EMP2) deficiency alters placental angiogenesis, mimicking features of human placental insufficiency.Dynamic modelling of the mTOR signalling network reveals complex emergent behaviours conferred by DEPTOR.Acquisition of Temporal HIF Transcriptional Activity Using a Secreted Luciferase Assay.Imaging of oxygen gradients in giant umbrella cells: an ex vivo PLIM study.Poor prognosis in human papillomavirus-positive oropharyngeal squamous cell carcinomas that overexpress hypoxia inducible factor-1α.Mathematical modelling of interacting mechanisms for hypoxia mediated cell cycle commitment for mesenchymal stromal cells.Angiogenic Factors produced by Hypoxic Cells are a leading driver of Anastomoses in Sprouting Angiogenesis-a computational study.Optimizing fluorescent protein expression for quantitative fluorescence microscopy and spectroscopy using herpes simplex thymidine kinase promoter sequences.Inhibition of HIF1α-Dependent Upregulation of Phospho-l-Plastin Resensitizes Multiple Myeloma Cells to Frontline Therapy.Analysis of Transcriptomes Reveals Divergent Adaptive Response to Hyper- and Hypo-Salinity in the Hong Kong Oyster,Effective Single-Step Posttranscriptional Dynamics Allowing for a Direct Maximum Likelihood Estimation of Transcriptional Activity and the Quantification of Sources of Gene Expression Variability with an Illustration for the Hypoxia and TNFα Regulat
P2860
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P2860
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
@en
A dynamic model of the hypoxia-inducible factor 1α
@nl
type
label
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
@en
A dynamic model of the hypoxia-inducible factor 1α
@nl
prefLabel
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
@en
A dynamic model of the hypoxia-inducible factor 1α
@nl
P2093
P50
P356
P1476
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
@en
P2093
Mario C Manresa
Susan F Fitzpatrick
Ulrike Bruning
P304
P356
10.1242/JCS.119974
P407
P50
P577
2013-02-06T00:00:00Z