about
NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomasTranscriptional repression of the mouse wee1 gene by TBP-related factor 2RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.ALK is a MYCN target gene and regulates cell migration and invasion in neuroblastoma.RUNX3 interacts with MYCN and facilitates protein degradation in neuroblastoma.NLRR1 enhances EGF-mediated MYCN induction in neuroblastoma and accelerates tumor growth in vivo.Expression of NLRR3 orphan receptor gene is negatively regulated by MYCN and Miz-1, and its downregulation is associated with unfavorable outcome in neuroblastoma.Positive auto-regulation of MYCN in human neuroblastoma.Plk1 regulates liver tumor cell death by phosphorylation of TAp63.Expression of TSLC1, a candidate tumor suppressor gene mapped to chromosome 11q23, is downregulated in unfavorable neuroblastoma without promoter hypermethylation.KIF1Bbeta functions as a haploinsufficient tumor suppressor gene mapped to chromosome 1p36.2 by inducing apoptotic cell death.DeltaNp63/BMP-7-dependent expression of matrilin-2 is involved in keratinocyte migration in response to wounding.TATA-binding Protein (TBP)-like Protein Is Engaged in Etoposide-induced Apoptosis through Transcriptional Activation of Human TAp63 Gene.Transcriptional regulation of tumor suppressor p53 by cAMP-responsive element-binding protein/AMP-activated protein kinase complex in response to glucose deprivation.Sp1-mediated transcriptional regulation of NFBD1/MDC1 plays a critical role in DNA damage response pathway.TAp63-dependent induction of growth differentiation factor 15 (GDF15) plays a critical role in the regulation of keratinocyte differentiation.NFBD1/MDC1 participates in the regulation of G2/M transition in mammalian cells.TAp63 represses transcription of MYCN/NCYM gene and its high levels of expression are associated with favorable outcome in neuroblastoma
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description
hulumtues
@sq
researcher
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wetenschapper
@nl
հետազոտող
@hy
name
Yusuke Suenaga
@ast
Yusuke Suenaga
@en
Yusuke Suenaga
@es
Yusuke Suenaga
@fr
Yusuke Suenaga
@nl
Yusuke Suenaga
@sl
type
label
Yusuke Suenaga
@ast
Yusuke Suenaga
@en
Yusuke Suenaga
@es
Yusuke Suenaga
@fr
Yusuke Suenaga
@nl
Yusuke Suenaga
@sl
prefLabel
Yusuke Suenaga
@ast
Yusuke Suenaga
@en
Yusuke Suenaga
@es
Yusuke Suenaga
@fr
Yusuke Suenaga
@nl
Yusuke Suenaga
@sl
P106
P1153
23098593300
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P31
P496
0000-0001-6902-5386