RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53. - Wikidata - awgldk - TriplyDB

RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.

RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.

http://www.wikidata.org/entity/Q33883483

about

Helicobacter pylori-induced inflammation and epigenetic changes during gastric carcinogenesis Novel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2 Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice.Clinicopathological significance and potential drug target of RUNX3 in breast cancer.RUNX3 Controls a Metastatic Switch in Pancreatic Ductal Adenocarcinoma RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC.RUNX3 is down-regulated in glioma by Myc-regulated miR-4295 The clinicopathological significance of RUNX3 hypermethylation and mRNA expression in human breast cancer, a meta-analysis.Apoptotic cell death in neuroblastoma.MicroRNA-185 regulates chemotherapeutic sensitivity in gastric cancer by targeting apoptosis repressor with caspase recruitment domain.p53: the attractive tumor suppressor in the cancer research field.RUNX family: Regulation and diversification of roles through interacting proteins.RUNX Family Participates in the Regulation of p53-Dependent DNA Damage Response.Role of p53 in Cell Death and Human Cancers.The RUNX family: developmental regulators in cancer.Runt-related transcription factor 1 (RUNX1) stimulates tumor suppressor p53 protein in response to DNA damage through complex formation and acetylation.Toxoplasma gondii Rhoptry Protein ROP16 Mediates Partially SH-SY5Y Cells Apoptosis and Cell Cycle Arrest by Directing Ser15/37 Phosphorylation of p53 Molecular mechanism underlying the antiproliferative effect of suppressor of cytokine signaling-1 in non-small-cell lung cancer cells.RUNX3 interacts with MYCN and facilitates protein degradation in neuroblastoma.Runt-related transcription factor 2 (RUNX2) inhibits p53-dependent apoptosis through the collaboration with HDAC6 in response to DNA damage.UnPAKing RUNX3 functions-Both sides of the coin.Genome profiling of pancreatic adenocarcinoma.RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer.Stepwise cumulation of RUNX3 methylation mediated by Helicobacter pylori infection contributes to gastric carcinoma progression.RUNX3 regulates CDKN1A transcription Truncated forms of RUNX3 Unlike Full Length Protein Alter Cell Proliferation in a TGF-β Context Dependent Manner.A cautionary tale of sense-antisense gene pairs: independent regulation despite inverse correlation of expression.Functional Analyses of RUNX3 and CaMKIINα in Ovarian Cancer Cell Lines Reveal Tumor-Suppressive Functions for CaMKIINα and Dichotomous Roles for RUNX3 Transcript Variants.RUNX3 binds TP53 Roles of RUNX in Solid Tumors.A Regulatory Role for RUNX1, RUNX3 in the Maintenance of Genomic Integrity.Runx3 and Cell Fate Decisions in Pancreas Cancer.RUNX3 and p53: How Two Tumor Suppressors Cooperate Against Oncogenic Ras?Impact of RUNX2 on drug-resistant human pancreatic cancer cells with p53 mutations.Of mice and men: the nonrandom genomic instability in hepatocarcinogenesis.

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P2860

RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.

http://www.wikidata.org/entity/Q33883483

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

RUNX3 modulates DNA damage-med ...... cts as a co-activator for p53.

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RUNX3 modulates DNA damage-med ...... cts as a co-activator for p53.

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type

label

RUNX3 modulates DNA damage-med ...... cts as a co-activator for p53.

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RUNX3 modulates DNA damage-med ...... cts as a co-activator for p53.

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prefLabel

RUNX3 modulates DNA damage-med ...... cts as a co-activator for p53.

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RUNX3 modulates DNA damage-med ...... cts as a co-activator for p53.

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JBC.M109.055525

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Journal of Biological Chemistry

P1476

RUNX3 modulates DNA damage-med ...... cts as a co-activator for p53.

@en

P2093

Akira Nakagawara

http://www.w3.org/2001/XMLSchema#string

Chizu Yamada

http://www.w3.org/2001/XMLSchema#string

Hajime Kageyama

http://www.w3.org/2001/XMLSchema#string

Hideki Kimura

http://www.w3.org/2001/XMLSchema#string

Ken-ichi Inoue

http://www.w3.org/2001/XMLSchema#string

Kiyohiro Ando

http://www.w3.org/2001/XMLSchema#string

Masaru Miyazaki

http://www.w3.org/2001/XMLSchema#string

Rintaro Okoshi

http://www.w3.org/2001/XMLSchema#string

Toshinori Ozaki

http://www.w3.org/2001/XMLSchema#string

Yoshiaki Ito

http://www.w3.org/2001/XMLSchema#string

P2860

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

p53 isoforms can regulate p53 transcriptional activity.

Regulation of p53 function and stability by phosphorylation

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

p53 mutations in human cancers

Causal relationship between the loss of RUNX3 expression and gastric cancer

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22

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285

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2010-03-30T00:00:00Z

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20353948

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phosphorylation

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2878082

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