Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation. - Wikidata - awgldk - TriplyDB

Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation.

Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation.

http://www.wikidata.org/entity/Q30505171

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Regulation of cilium length and intraflagellar transport by the RCK-kinases ICK and MOK in renal epithelial cells The Cilium: Cellular Antenna and Central Processing Unit Left-right asymmetry in the light of TOR: An update on what we know so far Inhibition of autophagy suppresses sertraline-mediated primary ciliogenesis in retinal pigment epithelium cells TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.The V-ATPase accessory protein Atp6ap1b mediates dorsal forerunner cell proliferation and left-right asymmetry in zebrafish.The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets.Kupffer's vesicle size threshold for robust left-right patterning of the zebrafish embryo.Characterization of Sin1 Isoforms Reveals an mTOR-Dependent and Independent Function of Sin1γ Mechanical properties of a primary cilium as measured by resonant oscillation.Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules.Both ciliary and non-ciliary functions of Foxj1a confer Wnt/β-catenin signaling in zebrafish left-right patterning.Autophagy and primary cilia: dual interplay Activation loop phosphorylation of a protein kinase is a molecular marker of organelle size that dynamically reports flagellar length.Primary cilia and kidney injury: current research status and future perspectives CHES1/FOXN3 regulates cell proliferation by repressing PIM2 and protein biosynthesis.Identification of Elongated Primary Cilia with Impaired Mechanotransduction in Idiopathic Scoliosis Patients.Primary ciliary dyskinesia: recent advances in epidemiology, diagnosis, management and relationship with the expanding spectrum of ciliopathy.The ciliary flow sensor and polycystic kidney disease.The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth A role for primary cilia in aortic valve development and disease.Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.Reduced cilia frequencies in human renal cell carcinomas versus neighboring parenchymal tissue.Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.Dynamics of cilia length in left-right development.Grk5l controls heart development by limiting mTOR signaling during symmetry breaking.The Bardet-Biedl syndrome-related protein CCDC28B modulates mTORC2 function and interacts with SIN1 to control cilia length independently of the mTOR complex TORC1-mediated protein synthesis regulates cilia size and function: implications for organelle size control by diverse signaling cascades.Axonemal dynein assembly requires the R2TP complex component Pontin.TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms.Cilia length and intraflagellar transport regulation by kinases PKG-1 and GCK-2 in C. elegans sensory neurons.Cell volume changes contribute to epithelial morphogenesis in zebrafish Kupffer's vesicle.Glucose deprivation induces primary cilium formation through mTORC1 inactivation.The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts.New class of transcription factors controls flagellar assembly by recruiting RNA polymerase II in Chlamydomonas.Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies.

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P2860

Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation.

http://www.wikidata.org/entity/Q30505171

description

2012 nî lūn-bûn

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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած

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Target-of-rapamycin complex 1 ...... protein synthesis regulation.

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Target-of-rapamycin complex 1 ...... protein synthesis regulation.

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Proceedings of the National Academy of Sciences of the United States of America

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Target-of-rapamycin complex 1 ...... protein synthesis regulation.

@en

P2093

Dennis R Diener

http://www.w3.org/2001/XMLSchema#string

Jade Li

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Joel L Rosenbaum

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Michael A Choma

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Shiaulou Yuan

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Zhaoxia Sun

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P2860

Functional genomic screen for modulators of ciliogenesis and cilium length

Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival

Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3

mTOR: from growth signal integration to cancer, diabetes and ageing

Ciliogenesis: building the cell's antenna.

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

The primary cilium: a signalling centre during vertebrate development

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

The tuberous sclerosis complex

FGF signalling during embryo development regulates cilia length in diverse epithelia.

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2021-2026

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scholarly article

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10.1073/PNAS.1112834109

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6

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109

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2012-01-23T00:00:00Z

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221808855

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22308353

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3277533

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