about
Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors.Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cellsER stress controls iron metabolism through induction of hepcidinLoss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in miceGeneration of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementationThe orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4Transcriptional regulation of the human hepatic lipase (LIPC) gene promoterCardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heartLight chain 1 of microtubule-associated protein 1B can negatively regulate the action of Pes1Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryosThe transcription factor GATA-6 regulates pathological cardiac hypertrophyThe MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion.Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesisPescadillo is essential for nucleolar assembly, ribosome biogenesis, and mammalian cell proliferationGATA4 is essential for formation of the proepicardium and regulates cardiogenesisIsoflurane preconditioning elicits competent endogenous mechanisms of protection from oxidative stress in cardiomyocytes derived from human embryonic stem cellsGeneration of mice harbouring a conditional loss-of-function allele of Gata6.Development of the mammalian liver and ventral pancreas is dependent on GATA4.Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratumHepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in miceGATA4 is essential for jejunal function in miceTranscriptional regulation of liver development.Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cellsGATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature miceBMPs on the road to hepatogenesis.Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liverThe Peroxisomal 3-keto-acyl-CoA thiolase B Gene Expression Is under the Dual Control of PPARα and HNF4α in the LiverSall4 overexpression blocks murine hematopoiesis in a dose-dependent manner.Identification of small molecules for human hepatocyte expansion and iPS differentiationA threshold of GATA4 and GATA6 expression is required for cardiovascular developmentMechanisms controlling early development of the liver.Gene targeting in the mouse: advances in introduction of transgenes into the genome by homologous recombination.Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice.Aneuploidy is permissive for hepatocyte-like cell differentiation from human induced pluripotent stem cells.HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells.Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient miceExpression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst.Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed CellsDesign of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like CellsModeling hepatitis C virus infection using human induced pluripotent stem cells.
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description
hulumtues
@sq
researcher
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wetenschapper
@nl
հետազոտող
@hy
name
Stephen A Duncan
@nl
Stephen A Duncan
@sl
Stephen A. Duncan
@en
Stephen A. Duncan
@es
Stephen Duncan
@fr
type
label
Stephen A Duncan
@nl
Stephen A Duncan
@sl
Stephen A. Duncan
@en
Stephen A. Duncan
@es
Stephen Duncan
@fr
prefLabel
Stephen A Duncan
@nl
Stephen A Duncan
@sl
Stephen A. Duncan
@en
Stephen A. Duncan
@es
Stephen Duncan
@fr
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P106
P1153
7202422893
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P496
0000-0002-2507-7827