SK2 channels are neuroprotective for ischemia-induced neuronal cell death - Wikidata - awgldk - TriplyDB

SK2 channels are neuroprotective for ischemia-induced neuronal cell death

SK2 channels are neuroprotective for ischemia-induced neuronal cell death

http://www.wikidata.org/entity/Q30512907

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Identification of the functional binding pocket for compounds targeting small-conductance Ca2+-activated potassium channels Unstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca2+-sensing and SK channel activation Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons Extracranial hypothermia during cardiac arrest and cardiopulmonary resuscitation is neuroprotective in vivo.Pro-inflammatory T-lymphocytes rapidly infiltrate into the brain and contribute to neuronal injury following cardiac arrest and cardiopulmonary resuscitation Increasing small conductance Ca2+-activated potassium channel activity reverses ischemia-induced impairment of long-term potentiation.Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex CyPPA, a Positive SK3/SK2 Modulator, Reduces Activity of Dopaminergic Neurons, Inhibits Dopamine Release, and Counteracts Hyperdopaminergic Behaviors Induced by Methylphenidate.Transcriptional Regulation of the Sodium-activated Potassium Channel SLICK (KCNT2) Promoter by Nuclear Factor-κB.Muscarinic M1 receptors modulate endotoxemia-induced loss of synaptic plasticity.Trafficking of intermediate (KCa3.1) and small (KCa2.x) conductance, Ca(2+)-activated K(+) channels: a novel target for medicinal chemistry efforts?Protective Roles for Potassium SK/K(Ca)2 Channels in Microglia and Neurons.GPER1/GPR30 activation improves neuronal survival following global cerebral ischemia induced by cardiac arrest in mice.Mitochondrial small conductance SK2 channels prevent glutamate-induced oxytosis and mitochondrial dysfunction.Sexually dimorphic response of TRPM2 inhibition following cardiac arrest-induced global cerebral ischemia in mice The therapeutic potential of small-conductance KCa2 channels in neurodegenerative and psychiatric diseases Inhibition of soluble epoxide hydrolase after cardiac arrest/cardiopulmonary resuscitation induces a neuroprotective phenotype in activated microglia and improves neuronal survival.Sirtuin-2 mediates male specific neuronal injury following experimental cardiac arrest through activation of TRPM2 ion channels.Therapeutic hypothermia protects against ischemia-induced impairment of synaptic plasticity following juvenile cardiac arrest in sex-dependent manner.A novel mouse model of pediatric cardiac arrest and cardiopulmonary resuscitation reveals age-dependent neuronal sensitivities to ischemic injury.Small-conductance calcium-activated potassium type 2 channels (SK2, KCa2.2) in human brain K(Ca)2 and k(ca)3 channels in learning and memory processes, and neurodegeneration.Global cerebral ischemia: synaptic and cognitive dysfunction.Calcium-activated potassium channels in ischemia reperfusion: a brief update.Activation of SK2 channels preserves ER Ca²⁺ homeostasis and protects against ER stress-induced cell death.SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake.Autonomous CaMKII Activity as a Drug Target for Histological and Functional Neuroprotection after Resuscitation from Cardiac Arrest.Osmotherapy With Hypertonic Saline Attenuates Global Cerebral Edema Following Experimental Cardiac Arrest via Perivascular Pool of Aquaporin-4 Activation of KCNN3/SK3/K(Ca)2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia.A selective M1 and M3 receptor antagonist, penehyclidine hydrochloride, prevents postischemic LTP: involvement of NMDA receptors.Delayed inhibition of tonic inhibition enhances functional recovery following experimental ischemic stroke.Minocycline attenuates microglial response and reduces neuronal death after cardiac arrest and cardiopulmonary resuscitation in mice.Conivaptan, a Selective Arginine Vasopressin V1a and V2 Receptor Antagonist Attenuates Global Cerebral Edema Following Experimental Cardiac Arrest via Perivascular Pool of Aquaporin-4.EEG power as a biomarker to predict the outcome after cardiac arrest and cardiopulmonary resuscitation induced global ischemia.

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P2860

SK2 channels are neuroprotective for ischemia-induced neuronal cell death

http://www.wikidata.org/entity/Q30512907

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

SK2 channels are neuroprotective for ischemia-induced neuronal cell death

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SK2 channels are neuroprotective for ischemia-induced neuronal cell death

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type

label

SK2 channels are neuroprotective for ischemia-induced neuronal cell death

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SK2 channels are neuroprotective for ischemia-induced neuronal cell death

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prefLabel

SK2 channels are neuroprotective for ischemia-induced neuronal cell death

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SK2 channels are neuroprotective for ischemia-induced neuronal cell death

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P1433

Journal of Cerebral Blood Flow & Metabolism

P1476

SK2 channels are neuroprotective for ischemia-induced neuronal cell death

@en

P2093

Carmen Ballesteros

http://www.w3.org/2001/XMLSchema#string

Chris T Bond

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Duane Allen

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James Maylie

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John P Adelman

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Julie Palmateer

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Masahiko Watanabe

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Masayuki Kuroiwa

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Paco S Herson

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Rafael Luján

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P2860

Heart Disease and Stroke Statistics--2010 Update: A Report From the American Heart Association

Neuroprotection for ischemic stroke: past, present and future

Preparation and pharmacokinetics of labeled derivatives of apamin

Control of electrical activity in central neurons by modulating the gating of small conductance Ca2+-activated K+ channels

Small conductance Ca2+-activated K+ channels modulate synaptic plasticity and memory encoding

Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia

Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

The SK2-long isoform directs synaptic localization and function of SK2-containing channels

A novel N-methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity.

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2302-2312

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10.1038/JCBFM.2011.90

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12

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P478

31

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2011-06-29T00:00:00Z

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51451701

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21712833

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3323193

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