Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory region
about
Small but Mighty: Nanoparticles Probe Cellular Signaling PathwaysPhage Selection of Bicyclic Peptide Ligands of the Notch1 Receptor.Mutational analysis of the Notch2 negative regulatory region identifies key structural elements for mechanical stability.iRhom2 mutation leads to aberrant hair follicle differentiation in mice.Dynamics of the BH3-Only Protein Binding Interface of Bcl-xL.Ligand-Independent Mechanisms of Notch Activity.A Mechanogenetic Toolkit for Interrogating Cell Signaling in Space and Time.Regulated unfolding of proteins in signalingPlatelet clearance via shear-induced unfolding of a membrane mechanoreceptor.Membrane tethered delta activates notch and reveals a role for spatio-mechanical regulation of the signaling pathway.Therapeutic modulation of Notch signalling--are we there yet?Significance of glycosylation in Notch signaling.Lighting Up the Force: Investigating Mechanisms of Mechanotransduction Using Fluorescent Tension Probes.Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch.Human NOTCH2 Is Resistant to Ligand-independent Activation by Metalloprotease Adam17.Regulated proteolysis of NOTCH2 and NOTCH3 receptors by ADAM10 and presenilins.Control of Adhesion GPCR Function Through Proteolytic Processing.Methods to investigate the structure and connectivity of the nervous system.Context-dependent function of ROS in the vascular endothelium: The role of the Notch pathway and shear stress.Insights into Notch3 activation and inhibition mediated by antibodies directed against its negative regulatory region.Monitoring cell-cell contacts in vivo in transgenic animals.Receptor-mediated cell mechanosensing.Substrate stiffness of endothelial cells directs LFA-1/ICAM-1 interaction: A physical trigger of immune-related diseases?Joining forces: integrating the mechanical and optical single molecule toolkitsCongenital diseases caused by defective -glycosylation of Notch receptors
P2860
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P2860
Direct observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory region
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Direct observation of proteoly ...... tch negative regulatory region
@ast
Direct observation of proteoly ...... tch negative regulatory region
@en
type
label
Direct observation of proteoly ...... tch negative regulatory region
@ast
Direct observation of proteoly ...... tch negative regulatory region
@en
prefLabel
Direct observation of proteoly ...... tch negative regulatory region
@ast
Direct observation of proteoly ...... tch negative regulatory region
@en
P2860
P356
P1476
Direct observation of proteoly ...... tch negative regulatory region
@en
P2093
Johanna M Avis
P2860
P304
P356
10.1073/PNAS.1205788109
P407
P577
2012-09-24T00:00:00Z