The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner.

The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner.

Item
http://www.wikidata.org/entity/Q30529641
Multiple tolerance defects contribute to the breach of B cell tolerance in New Zealand Black chromosome 1 congenic miceB cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance.Significant Reductions in Mortality in Hospitalized Patients with Systemic Lupus Erythematosus in Washington State from 2003 to 2011Estrogen receptor alpha signaling promotes Sle1-induced loss of tolerance and immune cell activation and is responsible for sex bias in B6.Sle1 congenic mice.Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity.Lupus-Prone Mice Resist Immune Regulation and Transplant Tolerance Induction.IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity.Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1-isoform of the Slamf6 receptorDysregulated Lymphoid Cell Populations in Mouse Models of Systemic Lupus Erythematosus.Spontaneous germinal centers and autoimmunity.Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling.Mer Receptor Tyrosine Kinase Signaling Prevents Self-Ligand Sensing and Aberrant Selection in Germinal Centers.CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice.Extensively re-organized systemic lymph nodes provide a feasible environment for self-reactivity in lupus-prone NZB × NZW F1 mice.The development of autoimmune features in aging mice is closely associated with alterations of the peripheral CD4⁺ T-cell compartment.
P2860

The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner.

Item
http://www.wikidata.org/entity/Q30529641
description
2012 nî lūn-bûn
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2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The lupus-prone NZM2410/NZW st ...... in a B cell-intrinsic manner.
@ast
The lupus-prone NZM2410/NZW st ...... in a B cell-intrinsic manner.
@en
type
label
The lupus-prone NZM2410/NZW st ...... in a B cell-intrinsic manner.
@ast
The lupus-prone NZM2410/NZW st ...... in a B cell-intrinsic manner.
@en
prefLabel
The lupus-prone NZM2410/NZW st ...... in a B cell-intrinsic manner.
@ast
The lupus-prone NZM2410/NZW st ...... in a B cell-intrinsic manner.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
The lupus-prone NZM2410/NZW st ...... in a B cell-intrinsic manner.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932