Low dystrophin levels increase survival and improve muscle pathology and function in dystrophin/utrophin double-knockout mice
about
Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapyThe Dystrophin Complex: Structure, Function, and Implications for TherapyConserved regions of the DMD 3' UTR regulate translation and mRNA abundance in cultured myotubesSpell Checking Nature: Versatility of CRISPR/Cas9 for Developing Treatments for Inherited Disorders.Adenoviral vectors encoding CRISPR/Cas9 multiplexes rescue dystrophin synthesis in unselected populations of DMD muscle cells.Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy.How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouseInhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy.2015 William Allan Award.In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.In vivo gene editing in dystrophic mouse muscle and muscle stem cells.Genomic removal of a therapeutic mini-dystrophin gene from adult mice elicits a Duchenne muscular dystrophy-like phenotypeCurrent Translational Research and Murine Models For Duchenne Muscular Dystrophy.Histopathological Evaluation of Skeletal Muscle with Specific Reference to Mouse Models of Muscular Dystrophy.Long-term dietary quercetin enrichment as a cardioprotective countermeasure in mdx mice.Uniform low-level dystrophin expression in the heart partially preserved cardiac function in an aged mouse model of Duchenne cardiomyopathy.Adaptive Immune Response Impairs the Efficacy of Autologous Transplantation of Engineered Stem Cells in Dystrophic Dogs.Lifelong quercetin enrichment and cardioprotection in Mdx/Utrn+/- mice.Accurate Dystrophin Quantification in Mouse Tissue; Identification of New and Evaluation of Existing Methods.A dystrophic Duchenne mouse model for testing human antisense oligonucleotides.Dystrophin levels and clinical severity in Becker muscular dystrophy patients.Repurposing Dantrolene for Long-Term Combination Therapy to Potentiate Antisense-Mediated DMD Exon Skipping in the mdx Mouse.Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy.Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice.Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular DystrophyAlterations in the muscle force transfer apparatus in aged rats during unloading and reloading: impact of microRNA-31CRISPR-SKIP: programmable gene splicing with single base editors
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P2860
Low dystrophin levels increase survival and improve muscle pathology and function in dystrophin/utrophin double-knockout mice
description
2013 nî lūn-bûn
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2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
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2013年论文
@wuu
name
Low dystrophin levels increase ...... /utrophin double-knockout mice
@ast
Low dystrophin levels increase ...... /utrophin double-knockout mice
@en
type
label
Low dystrophin levels increase ...... /utrophin double-knockout mice
@ast
Low dystrophin levels increase ...... /utrophin double-knockout mice
@en
prefLabel
Low dystrophin levels increase ...... /utrophin double-knockout mice
@ast
Low dystrophin levels increase ...... /utrophin double-knockout mice
@en
P2093
P2860
P50
P356
P1433
P1476
Low dystrophin levels increase ...... /utrophin double-knockout mice
@en
P2093
Courtney Young
Hans Heemskerk
Maaike van Putten
Margriet Hulsker
Vishna D Nadarajah
P2860
P304
P356
10.1096/FJ.12-224170
P407
P577
2013-03-04T00:00:00Z