B cells use mechanical energy to discriminate antigen affinities.
about
The germinal center antibody response in health and diseaseMechanical regulation of T-cell functionsMolecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapseThe RhoA-ROCK pathway in the regulation of T and B cell responsesPolarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse.CD28 and CD3 have complementary roles in T-cell traction forces.Germinal center B cells recognize antigen through a specialized immune synapse architecture.A Rough Energy Landscape to Describe Surface-Linked Antibody and Antigen Bond Formation.Vamp-7-dependent secretion at the immune synapse regulates antigen extraction and presentation in B-lymphocytes.How advances in immunology provide insight into improving vaccine efficacy.Force is a signal that cells cannot ignore.Single Molecule Fluorescence Microscopy on Planar Supported Bilayers.Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.The activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold.The HIV-1 envelope protein gp120 is captured and displayed for B cell recognition by SIGN-R1(+) lymph node macrophages.Supported Lipid Bilayer Technology for the Study of Cellular Interfaces.Comprehensive Analysis of Immunological Synapse Phenotypes Using Supported Lipid Bilayers.Lipid raft-dependent plasma membrane repair interferes with the activation of B lymphocytesUtilization of a photoactivatable antigen system to examine B-cell probing termination and the B-cell receptor sorting mechanisms during B-cell activation.Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell KillingA mechanobiological perspective on cadherins and the actin-myosin cytoskeletonTo use or not to use the force: How B lymphocytes extract surface-tethered antigensCocapture of cognate and bystander antigens can activate autoreactive B cells.The pivotal position of the actin cytoskeleton in the initiation and regulation of B cell receptor activation.Actin-mediated feedback loops in B-cell receptor signaling.Class I myosins in B-cell physiology: functions in spreading, immune synapses, motility, and vesicular traffic.Early BCR Events and Antigen Capture, Processing, and Loading on MHC Class II on B Cells.The actin cytoskeleton coordinates the signal transduction and antigen processing functions of the B cell antigen receptor.Molecular control of B cell activation and immunological synapse formation.Force-induced remodelling of proteins and their complexesB Cells use Conserved Polarity Cues to Regulate Their Antigen Processing and Presentation Functions.Molecular Mechanisms of B Cell Antigen Gathering and Endocytosis.Dynamics of the membrane-cytoskeleton interface in MHC class II-restricted antigen presentation.Germinal Center B Cell Dynamics.Mechanical Communication at the Immunological Synapse.Antigen-specific B lymphocytes acquire proteoglycan aggrecan from cartilage extracellular matrix resulting in antigen presentation and CD4+ T-cell activation.The Other Function: Class II-Restricted Antigen Presentation by B Cells.Supported lipid bilayer platforms to probe cell mechanobiology.Cytoskeletal control of B cell responses to antigens.How germinal centers evolve broadly neutralizing antibodies: the breadth of the follicular helper T cell response.
P2860
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P2860
B cells use mechanical energy to discriminate antigen affinities.
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
B cells use mechanical energy to discriminate antigen affinities.
@ast
B cells use mechanical energy to discriminate antigen affinities.
@en
type
label
B cells use mechanical energy to discriminate antigen affinities.
@ast
B cells use mechanical energy to discriminate antigen affinities.
@en
prefLabel
B cells use mechanical energy to discriminate antigen affinities.
@ast
B cells use mechanical energy to discriminate antigen affinities.
@en
P2093
P2860
P50
P356
P1433
P1476
B cells use mechanical energy to discriminate antigen affinities.
@en
P2093
Antonio Casal
Bhakti Mistry
Elizabeth Natkanski
P2860
P304
P356
10.1126/SCIENCE.1237572
P407
P577
2013-05-16T00:00:00Z