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Direct interaction of Syk and Lyn protein tyrosine kinases in rat basophilic leukemia cells activated via type I Fc epsilon receptors.The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens.Intrinsic properties of immunoglobulin IgG1 isotype-switched B cell receptors promote microclustering and the initiation of signalingB cells use mechanical energy to discriminate antigen affinities.Germinal center B cells recognize antigen through a specialized immune synapse architecture.The initiation of antigen-induced B cell antigen receptor signaling viewed in living cells by fluorescence resonance energy transfer.A conformation-induced oligomerization model for B cell receptor microclustering and signalingA method for analyzing protein-protein interactions in the plasma membrane of live B cells by fluorescence resonance energy transfer imaging as acquired by total internal reflection fluorescence microscopy.Change we can believe in--of the conformational type. Workshop on the Initiation of Antigen Receptor SignalingImaging B-cell receptor signaling by single-molecule techniques.The molecular assembly and organization of signaling active B-cell receptor oligomers.Force generation in B-cell synapses: mechanisms coupling B-cell receptor binding to antigen internalization and affinity discrimination.Cytoskeletal control of B cell responses to antigens.B cell antigen extraction is regulated by physical properties of antigen-presenting cells.Signaling assemblies formed in mast cells activated via Fcepsilon receptor I dimers.DNA-Based Probes for Measuring Mechanical Forces in Cell-Cell Contacts: Application to B Cell Antigen Extraction from Immune Synapses.Myosin IIa Promotes Antibody Responses by Regulating B Cell Activation, Acquisition of Antigen, and Proliferation.Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated AntigensProtein tyrosine kinase Syk is involved in Thy-1 signaling in rat basophilic leukemia cellsB cells extract antigens at Arp2/3-generated actin foci interspersed with linear filamentsIntrinsic properties of human germinal center B cells set antigen affinity thresholdsMechanics of antigen extraction in the B cell synapseMonocytes work harder under pressureMHC class II cell-autonomously regulates self-renewal and differentiation of normal and malignant B cells
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description
researcher ORCID ID = 0000-0003-4693-7299
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wetenschapper
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name
Pavel Tolar
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Pavel Tolar
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Pavel Tolar
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Pavel Tolar
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type
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Pavel Tolar
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Pavel Tolar
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Pavel Tolar
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Pavel Tolar
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Pavel Tolar
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Pavel Tolar
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Pavel Tolar
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Pavel Tolar
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0000-0003-4693-7299