DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity - Wikidata - awgldk - TriplyDB

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

http://www.wikidata.org/entity/Q30608340

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T Lymphocyte Migration: An Action Movie Starring the Actin and Associated Actors.A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction DOCK8 regulates signal transduction events to control immunity Recurrent and Sustained Viral Infections in Primary Immunodeficiencies.T cells require DOCK8 for flexibility and function.Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration.Delayed control of herpes simplex virus infection and impaired CD4(+) T-cell migration to the skin in mouse models of DOCK8 deficiency Recurrent viral infections associated with a homozygous CORO1A mutation that disrupts oligomerization and cytoskeletal association Recent Advances in DOCK8 Immunodeficiency Syndrome.The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells.DOCK 8 Deficiency, EBV+ Lymphomatoid Granulomatosis, and Intrafamilial Variation in Presentation.Studying human immunodeficiencies in humans: advances in fundamental concepts and therapeutic interventions.Chemokines, their receptors and human disease: the good, the bad and the itchy.Hyper-IgE Syndromes and the Lung.Atopic Dermatitis and Allergic Urticaria: Cutaneous Manifestations of Immunodeficiency.Current Status of Dedicator of Cytokinesis-Associated Immunodeficiency: DOCK8 and DOCK2.Genetics of eosinophilic esophagitis.DOCK8 deficiency: Insights into pathophysiology, clinical features and management.Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation.DOCK8 Drives Src-Dependent NK Cell Effector Function.Dedicator of cytokinesis 8 regulates signal transducer and activator of transcription 3 activation and promotes TH17 cell differentiation.Pathogenesis of infections in HIV-infected individuals: insights from primary immunodeficiencies.Molecular targets and signaling pathways regulated by nuclear translocation of syndecan-1.DOCK8 Deficiency Presenting as an IPEX-Like Disorder.DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs.IL-15 supports the generation of protective lung-resident memory CD4 T cells.DOCK8 Protein Regulates Macrophage Migration through Cdc42 Protein Activation and LRAP35a Protein Interaction.DOCK8 regulates fitness and function of regulatory T cells through modulation of IL-2 signaling.Primary atopic disorders.Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis.Interaction of septin 7 and DOCK8 in equine lymphocytes reveals novel insights into signaling pathways associated with autoimmunity

P2860

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P2860

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

http://www.wikidata.org/entity/Q30608340

description

2014 nî lūn-bûn

@nan

2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

@ast

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

@en

type

label

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

@ast

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

@en

prefLabel

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

@ast

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

@en

P1433

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P1476

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P1433

Journal of Experimental Medicine

P1476

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity

@en

P2093

Alexandra F Freeman

http://www.w3.org/2001/XMLSchema#string

Christopher G Dove

http://www.w3.org/2001/XMLSchema#string

Dara M Strauss-Albee

http://www.w3.org/2001/XMLSchema#string

Devon B Chandler-Brown

http://www.w3.org/2001/XMLSchema#string

Greg Crawford

http://www.w3.org/2001/XMLSchema#string

Helen C Su

http://www.w3.org/2001/XMLSchema#string

Helen F Matthews

http://www.w3.org/2001/XMLSchema#string

Huie Jing

http://www.w3.org/2001/XMLSchema#string

Judith N Mandl

http://www.w3.org/2001/XMLSchema#string

Jyh Liang Hor

http://www.w3.org/2001/XMLSchema#string

P2860

DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity

Combined immunodeficiency associated with DOCK8 mutations

GEF what? Dock180 and related proteins help Rac to polarize cells in new ways

DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

Tuning of antigen sensitivity by T cell receptor-dependent negative feedback controls T cell effector function in inflamed tissues.

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses.

Rho GTPases: biochemistry and biology

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

P304

2549-2566

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.20141307

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P407

P433

13

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P478

211

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P50

Scott N. Mueller

Heardley M Murdock

Jordan A Garcia

P577

2014-11-24T00:00:00Z

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P5875

268874808

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25422492

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P932

4267229

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