about
Some vexations that challenge viral immunologySkin CD4(+) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation.Distinct APC subtypes drive spatially segregated CD4+ and CD8+ T-cell effector activity during skin infection with HSV-1Persistence of skin-resident memory T cells within an epidermal niche.DOCK8 regulates lymphocyte shape integrity for skin antiviral immunityIn vivo imaging of the T cell response to infection.Immunization with live attenuated influenza viruses that express altered NS1 proteins results in potent and protective memory CD8+ T-cell responsesShort-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantationPD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.The early expression of glycoprotein B from herpes simplex virus can be detected by antigen-specific CD8+ T cells.Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infectionStromal cell contributions to the homeostasis and functionality of the immune system.Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation.Maintenance of T cell function in the face of chronic antigen stimulation and repeated reactivation for a latent virus infection.The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens.Lymphoid stroma in the initiation and control of immune responses.Neutrophils are dispensable in the modulation of T cell immunity against cutaneous HSV-1 infection.Peripheral tissue surveillance and residency by memory T cells.Memory T cell subsets, migration patterns, and tissue residence.Tissue-resident T cells: dynamic players in skin immunity.Tissue-resident memory T cells: local specialists in immune defence.CD4(+) T-cell help amplifies innate signals for primary CD8(+) T-cell immunity.Qualitatively different memory CD8+ T cells are generated after lymphocytic choriomeningitis virus and influenza virus infections.Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation.Infection Programs Sustained Lymphoid Stromal Cell Responses and Shapes Lymph Node Remodeling upon Secondary Challenge.Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.Spatiotemporally Distinct Interactions with Dendritic Cell Subsets Facilitates CD4+ and CD8+ T Cell Activation to Localized Viral Infection.Targeting Antigen to Clec9A Primes Follicular Th Cell Memory Responses Capable of Robust Recall.Skin DCs cluster for efficient T cell activation.Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.Grand Challenges in Immunological Memory.Characterization of two TCR transgenic mouse lines specific for herpes simplex virus.Dermal regulatory T cells display distinct migratory behavior that is modulated during adaptive and innate inflammation.Spreading the load: Antigen transfer between migratory and lymph node-resident dendritic cells promotes T-cell priming.Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses.Migratory CD11b+ conventional dendritic cells induce T follicular helper cell-dependent antibody responses.Optimization of TCR transgenic T cells for in vivo tracking of immune responses.Different patterns of peripheral migration by memory CD4+ and CD8+ T cells.Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Scott N Mueller
@nl
Scott N Mueller
@sl
Scott N. Mueller
@en
Scott N. Mueller
@es
type
label
Scott N Mueller
@nl
Scott N Mueller
@sl
Scott N. Mueller
@en
Scott N. Mueller
@es
prefLabel
Scott N Mueller
@nl
Scott N Mueller
@sl
Scott N. Mueller
@en
Scott N. Mueller
@es
P1053
B-1918-2012
P106
P1153
7202422141
P21
P31
P3829
P496
0000-0002-3838-3989