Nuclease P1 digestion combined with tandem mass spectrometry for the structure determination of DNA photoproducts.
about
Generation of 5-(2'-deoxycytidyl)methyl radical and the formation of intrastrand cross-link lesions in oligodeoxyribonucleotidesMass spectrometry for the assessment of the occurrence and biological consequences of DNA adductsDetermination of photomodified oligodeoxynucleotides by exonuclease digestion, matrix-assisted laser desorption/ionization and post-source decay mass spectrometry.Studies on the chemical synthesis of oligodeoxynucleotides containing the s5T(6-4)T photoproduct: side reactions derived from the methylsulfenyl thiol protection elucidated by MALDI mass spectrometry.A new photoproduct of 5-methylcytosine and adenine characterized by high-performance liquid chromatography and mass spectrometryCharacterization of oligodeoxynucleotides and modifications by 193 nm photodissociation and electron photodetachment dissociation.Hybrid activation methods for elucidating nucleic acid modificationsSynergistic modulation of cyclobutane pyrimidine dimer photoproduct formation and deamination at a TmCG site over a full helical DNA turn in a nucleosome core particle.Inter-strand photoproducts are produced in high yield within A-DNA exposed to UVC radiationPreparation of site-specific T=mCG cis-syn cyclobutane dimer-containing template and its error-free bypass by yeast and human polymerase ηPhotocrosslinking of human telomeric G-quadruplex loops by anti cyclobutane thymine dimer formationEffect of sequence and metal ions on UVB-induced anti cyclobutane pyrimidine dimer formation in human telomeric DNA sequences.The variety of UV-induced pyrimidine dimeric photoproducts in DNA as shown by chromatographic quantification methods.Acceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots.Structure determination of an interstrand-type cis-anti cyclobutane thymine dimer produced in high yield by UVB light in an oligodeoxynucleotide at acidic pH.Fragmentation of electrospray-produced oligodeoxynucleotide ions adducted to metal ions.Fragmentation of photomodified oligodeoxynucleotides adducted with metal ions in an electrospray-ionization ion-trap mass spectrometer.N4-methylation of cytosine drastically favors the formation of (6-4) photoproducts in a TCG context.Evidence for Reverse Hoogsteen Hairpin Intermediates in the Photocrosslinking of Human Telomeric DNA Sequences.Characterization of activation energy distribution for ultraviolet irradiation of T-rich oligonucleotide using high-performance liquid chromatography electrospray ionization mass spectrometry tandem mass spectrometry.Formation of the Main UV-induced Thymine Dimeric Lesions within Isolated and Cellular DNA as Measured by High Performance Liquid Chromatography-Tandem Mass Spectrometry
P2860
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P2860
Nuclease P1 digestion combined with tandem mass spectrometry for the structure determination of DNA photoproducts.
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Nuclease P1 digestion combined ...... mination of DNA photoproducts.
@ast
Nuclease P1 digestion combined ...... mination of DNA photoproducts.
@en
type
label
Nuclease P1 digestion combined ...... mination of DNA photoproducts.
@ast
Nuclease P1 digestion combined ...... mination of DNA photoproducts.
@en
prefLabel
Nuclease P1 digestion combined ...... mination of DNA photoproducts.
@ast
Nuclease P1 digestion combined ...... mination of DNA photoproducts.
@en
P2093
P356
P1476
Nuclease P1 digestion combined ...... mination of DNA photoproducts.
@en
P2093
P304
P356
10.1021/TX9900831
P577
1999-11-01T00:00:00Z