Acceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots.
about
Guanine holes are prominent targets for mutation in cancer and inherited diseaseA new photoproduct of 5-methylcytosine and adenine characterized by high-performance liquid chromatography and mass spectrometryReactivity of damaged pyrimidines: DNA cleavage via hemiaminal formation at the C4 positions of the saturated thymine of spore photoproduct and dihydrouridine.Methyl CpG binding protein 2 (MeCP2) enhances photodimer formation at methyl-CpG sites but suppresses dimer deamination.Synergistic modulation of cyclobutane pyrimidine dimer photoproduct formation and deamination at a TmCG site over a full helical DNA turn in a nucleosome core particle.Rotational position of a 5-methylcytosine-containing cyclobutane pyrimidine dimer in a nucleosome greatly affects its deamination rate.UV signature mutations.Preparation of site-specific T=mCG cis-syn cyclobutane dimer-containing template and its error-free bypass by yeast and human polymerase ηRapid deamination of cyclobutane pyrimidine dimer photoproducts at TCG sites in a translationally and rotationally positioned nucleosome in vivo.Sequence-dependent thymine dimer formation and photoreversal rates in double-stranded DNAThe Genomic Impact of DNA CpG Methylation on Gene Expression; Relationships in Prostate CancerPhotoinduced damage to cellular DNA: direct and photosensitized reactions.Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin.Quick, Selective and Reversible Photocrosslinking Reaction between 5-Methylcytosine and 3-Cyanovinylcarbazole in DNA Double Strand.Further assessment of exome-wide UVR footprints in melanoma and their possible relevance.A cyclobutane thymine-N4-methylcytosine dimer is resistant to hydrolysis but strongly blocks DNA synthesis.Extremophiles: radiation resistance microbial reserves and therapeutic implications.Cytosine containing dipyrimidine sites can be hotspots of cyclobutane pyrimidine dimer formation after UVB exposure.N4-methylation of cytosine drastically favors the formation of (6-4) photoproducts in a TCG context.Conformational and electronic effects on the formation of anti cyclobutane pyrimidine dimers in G-quadruplex structures.Evidence for Reverse Hoogsteen Hairpin Intermediates in the Photocrosslinking of Human Telomeric DNA Sequences.
P2860
Q28533852-3DF0CD27-DFDA-4B19-BC98-6D1D06280107Q33729312-6F3EF92C-8CDC-4F17-BE57-2754AE72CA4DQ34282644-57F36B12-E45C-4B37-9140-C2265FFA2921Q34298141-7E3D132E-A304-4BDA-A4F4-2AEBFE9EF036Q34579704-95D13AD6-44A7-407E-8B3E-0353A0334078Q34676045-C0685C2C-B794-4B06-9931-48C8348FD61DQ34963798-6E1EC6C6-3DC3-451E-9941-3777DA2743EEQ35868158-6D1DB463-B941-4524-8E70-BB4E9A8CE621Q36283708-E29D5DF0-0ECB-4311-90CB-077948438B87Q37274414-C2CA7CBD-C8B5-47C9-814C-CBF2669F930DQ37729422-E29D31E7-3F0B-4E83-8F8D-B9185B291682Q38025191-61D6C152-BAC5-42CA-BB66-A387447C4D2BQ38937094-79B9FC27-1CC8-4EC3-B526-13D851198384Q40043212-FECF331B-3793-4CCB-A5FB-F54FB45A4DD6Q40354559-33AD4144-EF91-4B42-A0FC-1B0F1E3E6D4AQ41941409-ADBDA7A7-091B-49DB-B792-839380ECCAD5Q43030502-8AA5ADC2-BD52-4597-A3BC-B05BEF59B249Q46518401-4BB2B4CC-C533-4D08-BCA5-55D540A7AE92Q46824930-C2A518E2-4D16-4529-BBD6-1863119BDC03Q48350237-E2B7A8DA-E736-4440-9CB2-83800ADBE225Q50123581-E02E07B9-BCD3-4805-9B88-B92ACCEDC2EE
P2860
Acceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Acceleration of 5-methylcytosi ...... uced C-to-T mutation hotspots.
@en
Acceleration of 5-methylcytosi ...... uced C-to-T mutation hotspots.
@nl
type
label
Acceleration of 5-methylcytosi ...... uced C-to-T mutation hotspots.
@en
Acceleration of 5-methylcytosi ...... uced C-to-T mutation hotspots.
@nl
prefLabel
Acceleration of 5-methylcytosi ...... uced C-to-T mutation hotspots.
@en
Acceleration of 5-methylcytosi ...... uced C-to-T mutation hotspots.
@nl
P2860
P1476
Acceleration of 5-methylcytosi ...... uced C-to-T mutation hotspots.
@en
P2093
Vincent J Cannistraro
P2860
P304
P356
10.1016/J.JMB.2009.07.048
P407
P577
2009-07-22T00:00:00Z