Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain.

Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain.

Item
http://www.wikidata.org/entity/Q30661998
Identification and Optimization of Inhibitors of Trypanosomal Cysteine Proteases: Cruzain, Rhodesain, and TbCatBIn Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruziStructural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoniA novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target.Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol proteaseCongopain from Trypanosoma congolense: drug target and vaccine candidate.Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones.Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1.Synthesis and Evaluation of Oxyguanidine Analogues of the Cysteine Protease Inhibitor WRR-483 against Cruzain.Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target.Synthesis of macrocyclic trypanosomal cysteine protease inhibitors.Angiotensin-converting enzyme limits inflammation elicited by Trypanosoma cruzi cysteine proteases: a peripheral mechanism regulating adaptive immunity via the innate kinin pathway.Trypanocidal drugs: mechanisms, resistance and new targets.Synthetic Medicinal Chemistry in Chagas' Disease: Compounds at The Final Stage of "Hit-To-Lead" Phase.Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri.Cysteine protease inhibitors as potential antiparasitic agents
P2860

Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain.

Item
http://www.wikidata.org/entity/Q30661998
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Potent second generation vinyl ...... mal cysteine protease cruzain.
@ast
Potent second generation vinyl ...... mal cysteine protease cruzain.
@en
type
label
Potent second generation vinyl ...... mal cysteine protease cruzain.
@ast
Potent second generation vinyl ...... mal cysteine protease cruzain.
@en
prefLabel
Potent second generation vinyl ...... mal cysteine protease cruzain.
@ast
Potent second generation vinyl ...... mal cysteine protease cruzain.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Potent second generation vinyl ...... mal cysteine protease cruzain.
@en
P2093
P304
P31
P356
10.1016/S0960-894X(01)00566-2
P407
P433
P478
P577
P698