The streptococcal hyaluronan synthases are inhibited by sulfhydryl-modifying reagents, but conserved cysteine residues are not essential for enzyme function.
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Size exclusion chromatography-multiangle laser light scattering analysis of hyaluronan size distributions made by membrane-bound hyaluronan synthase.Quantitative continuous assay for hyaluronan synthaseIdentification of a membrane-localized cysteine cluster near the substrate-binding sites of the Streptococcus equisimilis hyaluronan synthaseHyaluronan synthase mediates dye translocation across liposomal membranes.Clustered Conserved Cysteines in Hyaluronan Synthase Mediate Cooperative Activation by Mg(2+) Ions and Severe Inhibitory Effects of Divalent CationsHyaluronan synthase polymerizing activity and control of product size are discrete enzyme functions that can be uncoupled by mutagenesis of conserved cysteinesAgarose and polyacrylamide gel electrophoresis methods for molecular mass analysis of 5- to 500-kDa hyaluronan.Hyaluronan molecular weight is controlled by UDP-N-acetylglucosamine concentration in Streptococcus zooepidemicus.Evaluation of critical structural elements of UDP-sugar substrates and certain cysteine residues of a vertebrate hyaluronan synthase.Alteration of polysaccharide size distribution of a vertebrate hyaluronan synthase by mutation.Hyaluronan synthase control of synthesis rate and hyaluronan product size are independent functions differentially affected by mutations in a conserved tandem B-X7-B motif.
P2860
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P2860
The streptococcal hyaluronan synthases are inhibited by sulfhydryl-modifying reagents, but conserved cysteine residues are not essential for enzyme function.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The streptococcal hyaluronan s ...... essential for enzyme function.
@ast
The streptococcal hyaluronan s ...... essential for enzyme function.
@en
type
label
The streptococcal hyaluronan s ...... essential for enzyme function.
@ast
The streptococcal hyaluronan s ...... essential for enzyme function.
@en
prefLabel
The streptococcal hyaluronan s ...... essential for enzyme function.
@ast
The streptococcal hyaluronan s ...... essential for enzyme function.
@en
P2093
P2860
P356
P1476
The streptococcal hyaluronan s ...... essential for enzyme function.
@en
P2093
Bruce A Baggenstoss
Kshama Kumari
Paul H Weigel
Valarie L Tlapak-Simmons
P2860
P304
13943-13951
P356
10.1074/JBC.M110638200
P407
P577
2002-01-17T00:00:00Z