Isolation of temperature-sensitive p53 mutations from a comprehensive missense mutation library.
about
Solution structure of p53 core domain: structural basis for its instability.Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancerGene medicine for cancer treatment: commercially available medicine and accumulated clinical data in Chinatp53 mutant zebrafish develop malignant peripheral nerve sheath tumors.Mutant TP53 posttranslational modifications: challenges and opportunities.Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation.Effects of temperature on the p53-DNA binding interactions and their dynamical behavior: comparing the wild type to the R248Q mutant.Neighborhood properties are important determinants of temperature sensitive mutations.High throughput RNAi screening identifies ID1 as a synthetic sick/lethal gene interacting with the common TP53 mutation R175H.Structural basis for understanding oncogenic p53 mutations and designing rescue drugs.Whole-genome cartography of p53 response elements ranked on transactivation potential.Investigating DNA Binding and Conformational Variation in Temperature Sensitive p53 Cancer Mutants Using QM-MM Simulations.Study of Association between Pre-Senile Cataracts and the Polymorphisms rs2228000 in XPC and rs1042522 in p53 in Spanish Population.Changing the p53 master regulatory network: ELEMENTary, my dear Mr Watson.Reactivation of mutant p53: molecular mechanisms and therapeutic potential.Integrated mRNA and microRNA transcriptome sequencing characterizes sequence variants and mRNA-microRNA regulatory network in nasopharyngeal carcinoma model systems.Update on oncolytic viral therapy - targeting angiogenesisTP53 mutants in the tower of babel of cancer progression.Viral gene therapy for head and neck cancer.TP53: an oncogene in disguise.Human transcription factors in yeast: the fruitful examples of P53 and NF-кB.rAd-p53 enhances the sensitivity of human gastric cancer cells to chemotherapy.High frequency of temperature-sensitive mutants of p53 in glioblastoma.IPH-926 lobular breast cancer cells harbor a p53 mutant with temperature-sensitive functional activity and allow for profiling of p53-responsive genes.p53-expressing conditionally replicative adenovirus CNHK500-p53 against hepatocellular carcinoma in vitro.Hsp90 is essential for restoring cellular functions of temperature-sensitive p53 mutant protein but not for stabilization and activation of wild-type p53: implications for cancer therapy.p53, p63 and p73 in the wonderland of S. cerevisiae.A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction.Differential effects of novel tumour-derived p53 mutations on the transformation of NIH-3T3 cells.Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer.
P2860
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P2860
Isolation of temperature-sensitive p53 mutations from a comprehensive missense mutation library.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Isolation of temperature-sensi ...... ive missense mutation library.
@ast
Isolation of temperature-sensi ...... ive missense mutation library.
@en
type
label
Isolation of temperature-sensi ...... ive missense mutation library.
@ast
Isolation of temperature-sensi ...... ive missense mutation library.
@en
prefLabel
Isolation of temperature-sensi ...... ive missense mutation library.
@ast
Isolation of temperature-sensi ...... ive missense mutation library.
@en
P2093
P2860
P356
P1476
Isolation of temperature-sensi ...... ive missense mutation library.
@en
P2093
Chikashi Ishioka
Kazuko Shiraishi
Kazunori Otsuka
Masato Sakayori
Motohiro Takeda
Noriaki Ohuchi
Ryunosuke Kanamaru
Shuang-Yin Han
Shunsuke Kato
Takanori Ishida
P2860
P304
P356
10.1074/JBC.M310815200
P407
P577
2003-10-13T00:00:00Z