Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation. - Wikidata - awgldk - TriplyDB

Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation.

Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation.

http://www.wikidata.org/entity/Q33865095

about

The anti-melanoma activity of dinaciclib, a cyclin-dependent kinase inhibitor, is dependent on p53 signaling The rebel angel: mutant p53 as the driving oncogene in breast cancer.TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage Efficacy and Molecular Mechanisms of Differentiated Response to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Models of p53-Mutated Triple-Negative Breast Cancer Two different, mutually exclusively distributed, TP53 mutations in ovarian and peritoneal tumor tissues of a serous ovarian cancer patient: indicative for tumor origin?A minimally invasive assay for individual assessment of the ATM/CHEK2/p53 pathway activity Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast genetics Study of Association between Pre-Senile Cataracts and the Polymorphisms rs2228000 in XPC and rs1042522 in p53 in Spanish Population.TP53 mutation, epithelial-mesenchymal transition, and stemlike features in breast cancer subtypes Impact of EGFR and p53 expressions on survival and quality of life in locally advanced oral squamous cell carcinoma patients treated with chemoradiation Low-level p53 expression changes transactivation rules and reveals superactivating sequences.The human TLR innate immune gene family is differentially influenced by DNA stress and p53 status in cancer cells.PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis.Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells.TP53 mutants in the tower of babel of cancer progression.FGFR2 Amplification in Colorectal Adenocarcinoma.Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells.DHFR-mediated effects of methotrexate in medulloblastoma and osteosarcoma cells: the same outcome of treatment with different doses in sensitive cell lines.Human transcription factors in yeast: the fruitful examples of P53 and NF-кB.Assessment of TP53 Polymorphisms and MDM2 SNP309 in Premenopausal Breast Cancer Risk.The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53.Genomic Analysis Revealed New Oncogenic Signatures in TP53-Mutant Hepatocellular Carcinoma.

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P2860

Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation.

http://www.wikidata.org/entity/Q33865095

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Altered-function p53 missense ...... le effects on transactivation.

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Altered-function p53 missense ...... le effects on transactivation.

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type

label

Altered-function p53 missense ...... le effects on transactivation.

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Altered-function p53 missense ...... le effects on transactivation.

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prefLabel

Altered-function p53 missense ...... le effects on transactivation.

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Altered-function p53 missense ...... le effects on transactivation.

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Molecular Cancer Research

P1476

Altered-function p53 missense ...... le effects on transactivation.

@en

P2093

Alberto Inga

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Jennifer J Jordan

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Kathleen Conway

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Lin Wu

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Lisa A Carey

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Michael A Resnick

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Sharon Edmiston

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P2860

p53 isoforms can regulate p53 transcriptional activity.

Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer.

Molecular portraits of human breast tumours

p53 functions through stress- and promoter-specific recruitment of transcription initiation components before and after DNA damage

Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

p53: puzzle and paradigm

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

The antioxidant function of the p53 tumor suppressor

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