Molecular mechanism of APC/C activation by mitotic phosphorylation.
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Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin LigationThe unconventional kinetoplastid kinetochore: from discovery toward functional understandingMolecular basis of APC/C regulation by the spindle assembly checkpoint.APC/CCdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity.WD40 domain of Apc1 is critical for the coactivator-induced allosteric transition that stimulates APC/C catalytic activity.Unravelling biological macromolecules with cryo-electron microscopy.Rottlerin inhibits cell growth and invasion via down-regulation of Cdc20 in glioma cellsBuilding a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex.The mitotic checkpoint complex (MCC): looking back and forth after 15 years.Delayed APC/C activation extends the first mitosis of mouse embryos.EMBuilder: A Template Matching-based Automatic Model-building Program for High-resolution Cryo-Electron Microscopy Maps.Molecular mechanism for the regulation of yeast separase by securin.APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability.BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling.Kinetochores accelerate or delay APC/C activation by directing Cdc20 to opposing fates.Cell Cycle Control by Nuclear Sequestration of CDC20 and CDH1 mRNA in Plant Stem Cells.A cell based, high throughput assay for quantitative analysis of Hedgehog pathway activation using a Smoothened activation sensor.Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing.Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C).Evolving Therapeutic Strategies to Exploit Chromosome Instability in Cancer.APC/CFZR-1 Controls SAS-5 Levels To Regulate Centrosome Duplication in Caenorhabditis elegans.Global gene expression analysis combined with a genomics approach for the identification of signal transduction networks involved in postnatal mouse myocardial proliferation and development.USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.Calibrated mitotic oscillator drives motile ciliogenesis.Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis.The PP2AB56 phosphatase promotes the association of Cdc20 with APC/C in mitosis.Protein Complexes in the Nucleus: The Control of Chromosome Segregation.Cdk1 phosphorylation of Esp1/Separase functions with PP2A and Slk19 to regulate pericentric Cohesin and anaphase onset.SUMO targets the APC/C to regulate transition from metaphase to anaphase.Sumoylation promotes optimal APC/C Activation and Timely Anaphase.Cell division: Mitotic regulation comes into focus.Peptide inhibitors of the anaphase promoting-complex that cause sensitivity to microtubule poison.High levels of histones promote whole-genome-duplications and trigger a Swe1WEE1-dependent phosphorylation of Cdc28CDK1.Dissecting ribosomal particles throughout the kingdoms of life using advanced hybrid mass spectrometry methods.Kinase and Phosphatase Cross-Talk at the Kinetochore.
P2860
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P2860
Molecular mechanism of APC/C activation by mitotic phosphorylation.
description
2016 nî lūn-bûn
@nan
2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Molecular mechanism of APC/C activation by mitotic phosphorylation.
@ast
Molecular mechanism of APC/C activation by mitotic phosphorylation.
@en
type
label
Molecular mechanism of APC/C activation by mitotic phosphorylation.
@ast
Molecular mechanism of APC/C activation by mitotic phosphorylation.
@en
prefLabel
Molecular mechanism of APC/C activation by mitotic phosphorylation.
@ast
Molecular mechanism of APC/C activation by mitotic phosphorylation.
@en
P2093
P2860
P50
P356
P1433
P1476
Molecular mechanism of APC/C activation by mitotic phosphorylation.
@en
P2093
Claudio Alfieri
David Barford
Leifu Chang
Mark Skehel
Sarah Maslen
P2860
P2888
P304
P356
10.1038/NATURE17973
P407
P577
2016-04-27T00:00:00Z
P6179
1016371067