Diverted total synthesis: preparation of a focused library of latrunculin analogues and evaluation of their actin-binding properties
about
Nature's bounty - drug discovery from the seaLatrunculin analogues with improved biological profiles by "diverted total synthesis": preparation, evaluation, and computational analysis.Chemo- and site-selective derivatizations of natural products enabling biological studies.Total synthesis of (+)-18-epi-latrunculol A: development of a synthetic route.Total syntheses and biological reassessment of lactimidomycin, isomigrastatin and congener glutarimide antibiotics.Natural product analogues: towards a blueprint for analogue-focused synthesis.Molecular editing and assessment of the cytotoxic properties of iejimalide and progeny.Actin-based cellular framework for glucose signaling by Arabidopsis hexokinase1.Alkyne metathesis on the rise.Inhibition of interdomain motion in g-actin by the natural product latrunculin: a molecular dynamics study.Total syntheses of the actin-binding macrolides latrunculin A, B, C, M, S and 16-epi-latrunculin B.
P2860
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P2860
Diverted total synthesis: preparation of a focused library of latrunculin analogues and evaluation of their actin-binding properties
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Diverted total synthesis: prep ...... their actin-binding properties
@ast
Diverted total synthesis: prep ...... their actin-binding properties
@en
type
label
Diverted total synthesis: prep ...... their actin-binding properties
@ast
Diverted total synthesis: prep ...... their actin-binding properties
@en
prefLabel
Diverted total synthesis: prep ...... their actin-binding properties
@ast
Diverted total synthesis: prep ...... their actin-binding properties
@en
P2093
P2860
P356
P1476
Diverted total synthesis: prep ...... their actin-binding properties
@en
P2093
Christophe Aïssa
Dominic De Souza
Douglas Kirk
Michaël D B Fenster
Oliver Müller
P2860
P304
P356
10.1073/PNAS.0501441102
P407
P577
2005-05-25T00:00:00Z