Actin-binding marine macrolides: total synthesis and biological importance.
about
Chemodiversity in freshwater and terrestrial cyanobacteria - a source for drug discoveryCrystal Structures of Monomeric Actin Bound to Cytochalasin DStructural and Biochemical Studies of Actin in Complex with Synthetic Macrolide Tail AnaloguesSynthetic polyamines: new compounds specific to actin dynamics for mammalian cell and fission yeastDiverted total synthesis: preparation of a focused library of latrunculin analogues and evaluation of their actin-binding propertiesAntifungal compounds from cyanobacteria.Marine-derived anticancer agents in clinical trials.Synthesis of antimicrofilament marine macrolides: synthesis and configurational assignment of a C5-C16 degradation fragment of reidispongiolide AThe dual mode of action of bistramide A entails severing of filamentous actin and covalent protein modification.Synthesis of a 35-member stereoisomer library of bistramide A: evaluation of effects on actin state, cell cycle and tumor cell growth.Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activityTotal synthesis of aplyronine CAplyronine A, a potent antitumour macrolide of marine origin, and the congeners aplyronines B-H: chemistry and biology.Actin structure and function.The thiopyran route to polypropionatesSequential catalysis for stereoselective synthesis of complex polyketides.Marine natural products that interfere with multiple cytoskeletal protein interactions.Design, synthesis, and biological evaluation of simplified side chain hybrids of the potent actin binding polyketides rhizopodin and bistramide.Synthetic studies toward the brasilinolides: controlled assembly of a protected C1-C38 polyol based on fragment union by complex aldol reactions.Boron enolate chemistry toward the syntheses of polyketide stereotetrads.Fluorescent aplyronine a: intracellular accumulation and disassembly of actin cytoskeleton in tumor cells.Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.The structural determinants of macrolide-actin binding: in silico insights.Formal Synthesis of Premisakinolide A and C(19)-C(32) of Swinholide A via Site-Selective C-H Allylation and Crotylation of Unprotected DiolsTotal Synthesis of Swinholide A: An Exposition in Hydrogen-Mediated C-C Bond FormationThe Potential of Indonesian Heterobranchs Found around Bunaken Island for the Production of Bioactive Compounds.An Expedient Total Synthesis of Chivosazole F: an Actin-Binding Antimitotic Macrolide from the Myxobacterium Sorangium Cellulosum.The Samholides, Swinholide Related Metabolites from a Marine Cyanobacterium cf. Phormidium sp.Reiterative epoxide-based strategies for the synthesis of stereo-n-ads and application to polypropionate synthesis. A Personal Account.Challenges and discoveries in the total synthesis of complex polyketide natural products.Modular total synthesis of rhizopodin: a highly potent G-actin dimerizing macrolide.Total syntheses of the actin-binding macrolides latrunculin A, B, C, M, S and 16-epi-latrunculin B.Directed hydrogenations and an ireland-claisen rearrangement linked to evans-tishchenko chemistry: the highly efficient total synthesis of the marine cyclodepsipeptide doliculide.Iriomoteolides: novel chemical tools to study actin dynamics.Catalytic Enantioselective Aldol Addition Reactions
P2860
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P2860
Actin-binding marine macrolides: total synthesis and biological importance.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Actin-binding marine macrolides: total synthesis and biological importance.
@ast
Actin-binding marine macrolides: total synthesis and biological importance.
@en
type
label
Actin-binding marine macrolides: total synthesis and biological importance.
@ast
Actin-binding marine macrolides: total synthesis and biological importance.
@en
prefLabel
Actin-binding marine macrolides: total synthesis and biological importance.
@ast
Actin-binding marine macrolides: total synthesis and biological importance.
@en
P356
P1476
Actin-binding marine macrolides: total synthesis and biological importance.
@en
P2093
Ian Paterson
Kap-Sun Yeung
P304
P356
10.1002/ANIE.200290057
P407
P577
2002-12-01T00:00:00Z