Heat shock protein 90: translation from cancer to Alzheimer's disease treatment? - Wikidata - awgldk - TriplyDB

Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

http://www.wikidata.org/entity/Q30855123

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Hsp90: A New Player in DNA Repair?Positive or negative involvement of heat shock proteins in multiple sclerosis pathogenesis: an overview Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90 Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate.Heat shock protein 90 in neurodegenerative diseases DAMPening inflammation by modulating TLR signalling.Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.A cross-species analysis method to analyze animal models' similarity to human's disease state.PINCH in the cellular stress response to tau-hyperphosphorylation.Collaboration of geldanamycin-activated P70S6K and Hsp70 against beta-amyloid-induced hippocampal apoptosis: an approach to long-term memory and learning Design, synthesis, and evaluation of small molecule Hsp90 probes.Involvement of molecular chaperones and the transcription factor Nrf2 in neuroprotection mediated by para-substituted-4,5-diaryl-3-thiomethyl-1,2,4-triazines Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach?Development of Noviomimetics as C-Terminal Hsp90 Inhibitors Promoting Neuronal Tolerance of Diabetic Stress: Modulating Molecular Chaperones.Clinical utility of neuroprotective agents in neurodegenerative diseases: current status of drug development for Alzheimer's, Parkinson's and Huntington's diseases, and amyotrophic lateral sclerosis.Association of heat-shock proteins in various neurodegenerative disorders: is it a master key to open the therapeutic door?The double-edged sword: conserved functions of extracellular hsp90 in wound healing and cancer.Synopsis on the linkage of Alzheimer's and Parkinson's disease with chronic diseases.Unfolding the promise of translational targeting in neurodegenerative disease.Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitors Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention.

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P2860

Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

http://www.wikidata.org/entity/Q30855123

description

2008 nî lūn-bûn

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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

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2008年論文

@zh-tw

2008年论文

@wuu

name

Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

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Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

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type

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Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

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Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

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Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

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Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

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1471-2202-9-S2-S7

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BMC Neuroscience

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Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

@en

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Anna Rodina

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Wenjie Luo

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Creative Commons Attribution 2.0 Generic

P2860

The Hallmarks of Cancer

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

Inflammation and Alzheimer's disease

Neurotoxicity induces cleavage of p35 to p25 by calpain

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK(+) CD30(+) lymphoma cells by the Hsp90 antagonist 17-allylamino,17-demethoxygeldanamy

Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stress

Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I

Stabilization and activation of p53 induced by Cdk5 contributes to neuronal cell death

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1471-2202-9-s2-s7

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10.1186/1471-2202-9-S2-S7

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9 Suppl 2

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Gabriela Chiosis

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2008-12-03T00:00:00Z

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1030978832

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19090995

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Alzheimer's disease

molecular chaperones

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2604891

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