Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer. - Wikidata - awgldk - TriplyDB

Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

http://www.wikidata.org/entity/Q30866782

about

Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors Pim-1 kinase as cancer drug target: An update MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells.Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity.A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53.Molecular genetics of prostate cancer: new prospects for old challenges The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.Genetic markers associated with early cancer-specific mortality following prostatectomy Molecular pathways and targets in prostate cancer Antioxidant treatment promotes prostate epithelial proliferation in Nkx3.1 mutant mice.PIM kinase inhibitor AZD1208 for treatment of MYC-driven prostate cancer Animal models relevant to human prostate carcinogenesis underlining the critical implication of prostatic stem/progenitor cells.Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.Signaling mechanisms coupled to CXCL12/CXCR4-mediated cellular proliferation are PTEN-dependent.Recent progress in mouse models for tumor suppressor genes and its implications in human cancer.Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer New connections between old pathways: PDK1 signaling promotes cellular transformation through PLK1-dependent MYC stabilization.Therapeutic Approaches Targeting MYC-Driven Prostate Cancer Novel roles of peroxiredoxins in inflammation, cancer and innate immunity.Modeling prostate cancer in mice: something old, something new, something premalignant, something metastatic.Current mouse and cell models in prostate cancer research.Mitochondrial AKAP1 supports mTOR pathway and tumor growth.SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis Modeling African American prostate adenocarcinoma by inducing defined genetic alterations in organoids MYC and Prostate Cancer Calcium and Nuclear Signaling in Prostate Cancer.Development of a stress response therapy targeting aggressive prostate cancer.The effect of endurance training with and without vitamin E on expression of p53 and PTEN tumor suppressing genes in prostate glands of male rats.

P2860

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P2860

Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

http://www.wikidata.org/entity/Q30866782

description

2009 nî lūn-bûn

@nan

2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

@ast

Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

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type

label

Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

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Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

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prefLabel

Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

@ast

Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

@en

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JOURNAL.PGEN.1000542

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Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

@en

P2093

Isam-Eldin A Eltoum

http://www.w3.org/2001/XMLSchema#string

Jie Wang

http://www.w3.org/2001/XMLSchema#string

Jongchan Kim

http://www.w3.org/2001/XMLSchema#string

Meejeon Roh

http://www.w3.org/2001/XMLSchema#string

Sarki A Abdulkadir

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P2860

The functional contrariety of JNK

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Differences in gene expression in prostate cancer, normal appearing prostate tissue adjacent to cancer and prostate tissue from cancer free organ donors

A genetic model for colorectal tumorigenesis

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

c-MYC: more than just a matter of life and death

The transcriptional targets of p53 in apoptosis control

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

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e1000542

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10.1371/JOURNAL.PGEN.1000542

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7

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