Use of transgenic animals for carcinogenicity testing: considerations and implications for risk assessment.

Use of transgenic animals for carcinogenicity testing: considerations and implications for risk assessment.

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http://www.wikidata.org/entity/Q30881821
PET/CT imaging of c-Myc transgenic mice identifies the genotoxic N-nitroso-diethylamine as carcinogen in a short-term cancer bioassayAnimal models used in identifying gender-related differences.The Trp53 hemizygous mouse in pharmaceutical development: points to consider for pathologists.The use of genetically modified mice in cancer risk assessment: challenges and limitations.Risk assessment in the genomic era.Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection.Historical perspective on the use of animal bioassays to predict carcinogenicity: evolution in design and recognition of utility.Twenty-six-Week carcinogenicity study of chloroform in CB6F1 rasH2-transgenic mice.Genetic interaction between the unstable v-Ha-RAS transgene (Tg.AC) and the murine Werner syndrome gene: transgene instability and tumorigenesis.Animal models for the study of childhood leukemia: considerations for model identification and optimization to identify potential risk factors.Interlaboratory comparison of short-term carcinogenicity studies using CB6F1-rasH2 transgenic mice.Mutation and overexpression of the transgene in ethylnitrosourea-induced tumors in mice carrying a human prototype c-Ha-ras gene.Scientific Opinion on the use of Resorcinol as a food additiveReduction in the number of animals and the evaluation period for the positive control group in Tg.rasH2 short-term carcinogenicity studies.An integrative test strategy for cancer hazard identification.
P2860

Use of transgenic animals for carcinogenicity testing: considerations and implications for risk assessment.

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http://www.wikidata.org/entity/Q30881821
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2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
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2000年論文
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2000年論文
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2000年论文
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Use of transgenic animals for ...... lications for risk assessment.
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Use of transgenic animals for ...... lications for risk assessment.
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Use of transgenic animals for ...... lications for risk assessment.
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Use of transgenic animals for ...... lications for risk assessment.
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10.1177/019262330002800320
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P698