Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection.
about
A data-based assessment of alternative strategies for identification of potential human cancer hazards.The safety of PolyGlycopleX (PGX) as shown in a 90-day rodent feeding study.Critical review of preclinical approaches to evaluate the potential of immunosuppressive drugs to influence human neoplasia.Historical perspective on the use of animal bioassays to predict carcinogenicity: evolution in design and recognition of utility.Opportunities for an alternative integrating testing strategy for carcinogen hazard assessment?Rodent models for the preclinical evaluation of drugs suitable for pharmacological intervention in aging.Interpreting stress responses during routine toxicity studies: a review of the biology, impact, and assessment.Application of a novel integrated toxicity testing strategy incorporating "3R" principles of animal research to evaluate the safety of a new agrochemical sulfoxaflor.Regulatory Forum Opinion Piece*: Retrospective Evaluation of Doses in the 26-week Tg.rasH2 Mice Carcinogenicity Studies: Recommendation to Eliminate High Doses at Maximum Tolerated Dose (MTD) in Future Studies.Origin of the TTC values for compounds that are genotoxic and/or carcinogenic and an approach for their re-evaluation.Immunotoxicologic effects of cyclosporine on tumor progression in models of squamous cell carcinoma and B-cell lymphoma in C3H mice.
P2860
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P2860
Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Issues in the design and inter ...... approaches to dose selection.
@en
type
label
Issues in the design and inter ...... approaches to dose selection.
@en
prefLabel
Issues in the design and inter ...... approaches to dose selection.
@en
P2093
P2860
P1476
Issues in the design and inter ...... : approaches to dose selection
@en
P2093
Abigail Jacobs
Angelo Turturro
Dale Hattis
David Jacobson-Kram
Diana Somers
Jerry Rice
Karen Ekelman
Karl Baetcke
Lorenz R Rhomberg
P2860
P304
P356
10.1080/10408440701524949
P407
P577
2007-01-01T00:00:00Z