Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium.
about
Fragment screening and HIV therapeuticsDistinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational SelectionDetecting Allosteric Sites of HIV-1 Reverse Transcriptase by X-ray Crystallographic Fragment ScreeningScreening a fragment cocktail library using ultrafiltration.Three-dimensional structures in the design of therapeutics targeting parasitic protozoa: reflections on the past, present and future.A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.Advantages of crystallographic fragment screening: functional and mechanistic insights from a powerful platform for efficient drug discovery.Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library.SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1.The calcium-dependent protein kinase 1 from Toxoplasma gondii as target for structure-based drug design.Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
P2860
Q26826945-FBED320E-AF55-407A-835F-D9BB31D49D83Q27671580-D4CAACDB-4142-4DD9-AC1F-F3E026B6A6B3Q27675974-358007E4-64D9-4263-A998-E7825B069BE3Q33959477-A3E3040F-873F-4D05-9070-AE5B769C7B43Q35592514-0A5DAB06-08B0-4C1B-B237-41CE5B355883Q35739221-D3EDE445-A267-4BF1-888B-3EE185902ACBQ35848043-E77F9507-B855-4CD6-8AB1-73E3357C6716Q36006936-F742E86A-359C-437A-A3DA-10FFCCE7FF7CQ36368024-26A34C7F-CDDD-4EB1-9142-CC78510F2D3CQ47345749-9A928AB7-8E99-4F9E-9DFB-B52074FC748AQ54295012-AD2348F7-DAFE-4684-A0A3-577C5DC36504
P2860
Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Fragment-based cocktail crysta ...... athogenic protozoa consortium.
@ast
Fragment-based cocktail crysta ...... athogenic protozoa consortium.
@en
type
label
Fragment-based cocktail crysta ...... athogenic protozoa consortium.
@ast
Fragment-based cocktail crysta ...... athogenic protozoa consortium.
@en
prefLabel
Fragment-based cocktail crysta ...... athogenic protozoa consortium.
@ast
Fragment-based cocktail crysta ...... athogenic protozoa consortium.
@en
P2093
P2860
P1476
Fragment-based cocktail crysta ...... athogenic protozoa consortium.
@en
P2093
Alberto Napuli
Angela Kelly
Christophe L M J Verlinde
Eric T Larson
Erkang Fan
Ethan A Merritt
Frank Zucker
Frederick S Buckner
Isolde Letrong
Jennifer Ross
P2860
P304
P356
10.2174/156802609790102383
P50
P577
2009-01-01T00:00:00Z