Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases
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Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene PromotersGenetic-epigenetic interactions in cis: a major focus in the post-GWAS eraTranscriptome Analysis of CD4+ T Cells in Coeliac Disease Reveals Imprint of BACH2 and IFNγ Regulation.Conserved 33-kb haplotype in the MHC class III region regulates chronic arthritisAn integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation.Novel identified associations of RGS1 and RASGRP1 variants in IgA Nephropathy.Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants.New Insights and Biomarkers for Type 1 Diabetes: Review for Scandinavian Journal of Immunology.Progress in understanding type 1 diabetes through its genetic overlap with other autoimmune diseases.Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations.Cis-regulatory evolution in a wild primate: Infection-associated genetic variation drives differential expression of MHC-DQA1 in vitro.Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.The impact of RGS and other G-protein regulatory proteins on Gαi-mediated signaling in immunity.The Ties That Bind: Mapping the Dynamic Enhancer-Promoter Interactome.Inherited diseases caused by mutations in cathepsin protease genes.Expression QTLs Mapping and Analysis: A Bayesian Perspective.Immunogenomic approaches to understand the function of immune disease variants.Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease.Chromosome contacts in activated T cells identify autoimmune disease candidate genes.Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types.Human Lung DNA Methylation Quantitative Trait Loci Colocalize with COPD Genome-wide Association Loci.Context-specific effects of genetic variants associated with autoimmune disease.A Bayesian Framework for Multiple Trait Colo-calization from Summary Association Statistics.Three-dimensional organization and dynamics of the genome.Genome-wide association studies of multiple sclerosis.Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.Co-occurring expression and methylation QTLs allow detection of common causal variants and shared biological mechanisms.Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissueLeveraging DNA-Methylation Quantitative-Trait Loci to Characterize the Relationship between Methylomic Variation, Gene Expression, and Complex Traits
P2860
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P2860
Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Integration of disease associa ...... es in immune-mediated diseases
@ast
Integration of disease associa ...... es in immune-mediated diseases
@en
type
label
Integration of disease associa ...... es in immune-mediated diseases
@ast
Integration of disease associa ...... es in immune-mediated diseases
@en
prefLabel
Integration of disease associa ...... es in immune-mediated diseases
@ast
Integration of disease associa ...... es in immune-mediated diseases
@en
P2860
P50
P356
P1476
Integration of disease associa ...... es in immune-mediated diseases
@en
P2093
Mary D Fortune
P2860
P304
P356
10.1093/HMG/DDV077
P577
2015-03-05T00:00:00Z