Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway.
about
Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.Granzyme B secretion by human memory CD4 T cells is less strictly regulated compared to memory CD8 T cells.Cytotoxic CD4 T Cells-Friend or Foe during Viral Infection?Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody.PI3K functions in cancer progression, anticancer immunity and immune evasion by tumors.The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells.Emerging roles of regulatory T cells in tumour progression and metastasis.Integrated Akt/PKB signaling in immunomodulation and its potential role in cancer immunotherapy.Tregs activated by bispecific antibodies: Killers or suppressors?Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells.Interleukin-4 Supports the Suppressive Immune Responses Elicited by Regulatory T Cells.Human regulatory T cells undergo self-inflicted damage via granzyme pathways upon activation.PI3K in cancer: its structure, activation modes and role in shaping tumor microenvironment.
P2860
Q35071060-24C0ACE5-C5B0-4316-9F7C-495B7037862CQ35269599-870A5F8F-D2FE-48DA-AE90-6BBCCDA0066AQ37597931-69FF9B2D-0FDC-4D0A-9CDB-E4731DD2D4CAQ37598166-98C119EC-C94A-45AF-80E9-0863A6BB4153Q37951937-EC4A77F7-B010-4A4A-88C4-856FD2AE6E6DQ38008355-E49AAEEF-E9C2-414E-8005-05456B98703AQ38264092-0FEA97A2-74BF-4965-8001-80D0DC707E11Q38526844-097A6D3F-4349-406A-AD08-CD97AF2A1235Q39836444-5BA73AF8-C146-450C-ABB7-EC833DFA9A4AQ41926775-29DDA3B9-E1AE-4712-8DA2-9BBC418BA270Q47189664-D3FC6DE1-5B40-4406-B26E-5D5DE29A134CQ47275057-93F248AD-278E-4A03-91F6-1EF741E93329Q47794089-79B54BE8-2FF5-465F-9DD8-7C035F6F8140
P2860
Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Induction of granzyme B expres ...... tors of the PI3K-mTOR pathway.
@ast
Induction of granzyme B expres ...... tors of the PI3K-mTOR pathway.
@en
type
label
Induction of granzyme B expres ...... tors of the PI3K-mTOR pathway.
@ast
Induction of granzyme B expres ...... tors of the PI3K-mTOR pathway.
@en
prefLabel
Induction of granzyme B expres ...... tors of the PI3K-mTOR pathway.
@ast
Induction of granzyme B expres ...... tors of the PI3K-mTOR pathway.
@en
P2860
P356
P1433
P1476
Induction of granzyme B expres ...... tors of the PI3K-mTOR pathway.
@en
P2093
Olga V Efimova
Todd W Kelley
P2860
P2888
P356
10.1186/1471-2172-10-59
P577
2009-11-22T00:00:00Z
P5875
P6179
1003870832