Predicting toxicokinetic parameters in humans from toxicokinetic data acquired from three small mammalian species.

Predicting toxicokinetic parameters in humans from toxicokinetic data acquired from three small mammalian species.

Item
http://www.wikidata.org/entity/Q30941085
Interspecies scaling: is a priori knowledge of cytochrome p450 isozymes involved in drug metabolism helpful in prediction of clearance in humans from animal data?Interspecies scaling and prediction of human clearance: comparison of small- and macro-molecule drugsPharmacokinetics and interspecies allometric scaling of ST-246, an oral antiviral therapeutic for treatment of orthopoxvirus infection.Data-derived safety factors for the evaluation of food additives and environmental contaminants.Physiologically based pharmacokinetics (PBPK).Development and utilization of physiologically based pharmacokinetic models for toxicological applications.Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance.Pentachlorophenol carcinogenicity: extrapolation of risk from mice to humans.Interspecies scaling: predicting clearance of drugs in humans. Three different approaches.Estimation of human drug clearance using multiexponential techniques.Prediction of metabolic drug clearance in humans: in vitro-in vivo extrapolation vs allometric scaling.Prediction of clearance in humans from in vitro human liver microsomes and allometric scaling. A comparative study of the two approaches.Interspecies scaling: predicting volumes, mean residence time and elimination half-life. Some suggestions.
P2860

Predicting toxicokinetic parameters in humans from toxicokinetic data acquired from three small mammalian species.

Item
http://www.wikidata.org/entity/Q30941085
description
1989 nî lūn-bûn
@nan
1989 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Predicting toxicokinetic param ...... three small mammalian species.
@ast
Predicting toxicokinetic param ...... three small mammalian species.
@en
type
label
Predicting toxicokinetic param ...... three small mammalian species.
@ast
Predicting toxicokinetic param ...... three small mammalian species.
@en
prefLabel
Predicting toxicokinetic param ...... three small mammalian species.
@ast
Predicting toxicokinetic param ...... three small mammalian species.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Predicting toxicokinetic param ...... three small mammalian species.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698