Rb+ flux through hERG channels affects the potency of channel blocking drugs: correlation with data obtained using a high-throughput Rb+ efflux assay.

Rb+ flux through hERG channels affects the potency of channel blocking drugs: correlation with data obtained using a high-throughput Rb+ efflux assay.

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http://www.wikidata.org/entity/Q30969045
Computer-based prediction of the drug proarrhythmic effect: problems, issues, known and suspected challengesA new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel.Profiling diverse compounds by flux- and electrophysiology-based primary screens for inhibition of human Ether-à-go-go related gene potassium channels.Investigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay.A highly selective mitochondria-targeting fluorescent K(+) sensor.An introduction to QT interval prolongation and non-clinical approaches to assessing and reducing riskCardiac slices as a predictive tool for arrhythmogenic potential of drugs and chemicals.Screening technologies for ion channel drug discovery.Advances in functional assays for high-throughput screening of ion channels targets.Predicting drug-induced QT prolongation and torsades de pointes: a review of preclinical endpoint measures.Targeting cardiac potassium channels for state-of-the-art drug discovery.Development of recombinant cell line co-expressing mutated Nav1.5, Kir2.1, and hERG for the safety assay of drug candidates.In Vitro and In Silico Risk Assessment in Acquired Long QT Syndrome: The Devil Is in the Details.
P2860

Rb+ flux through hERG channels affects the potency of channel blocking drugs: correlation with data obtained using a high-throughput Rb+ efflux assay.

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http://www.wikidata.org/entity/Q30969045
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Rb+ flux through hERG channels ...... h-throughput Rb+ efflux assay.
@ast
Rb+ flux through hERG channels ...... h-throughput Rb+ efflux assay.
@en
type
label
Rb+ flux through hERG channels ...... h-throughput Rb+ efflux assay.
@ast
Rb+ flux through hERG channels ...... h-throughput Rb+ efflux assay.
@en
prefLabel
Rb+ flux through hERG channels ...... h-throughput Rb+ efflux assay.
@ast
Rb+ flux through hERG channels ...... h-throughput Rb+ efflux assay.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P5875
P698
P356
P1433
P1476
Rb+ flux through hERG channels ...... h-throughput Rb+ efflux assay.
@en
P2093
P304
P31
P356
P433
P478
P577
P5875
P698