Boosting of SIV-specific immune responses in rhesus macaques by repeated administration of Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinants.
about
Challenges in mucosal HIV vaccine development: lessons from non-human primate modelsHIV-1 Tat-based vaccines: an overview and perspectives in the field of HIV/AIDS vaccine development.Construction and immunogenicity of replication-competent adenovirus 5 host range mutant recombinants expressing HIV-1 gp160 of SF162 and TV1 strains.IIIa deleted adenovirus as a single-cycle genome replicating vector.HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaquesA DNA prime-oral Listeria boost vaccine in rhesus macaques induces a SIV-specific CD8 T cell mucosal response characterized by high levels of alpha4beta7 integrin and an effector memory phenotype.Improved protection of rhesus macaques against intrarectal simian immunodeficiency virus SIV(mac251) challenge by a replication-competent Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinant priming/gp120 boosting regimen.Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges.Limited immunogenicity of HIV CD8+ T-cell epitopes in acute Clade C virus infectionPotent, persistent induction and modulation of cellular immune responses in rhesus macaques primed with Ad5hr-simian immunodeficiency virus (SIV) env/rev, gag, and/or nef vaccines and boosted with SIV gp120.A replication-competent adenovirus-human immunodeficiency virus (Ad-HIV) tat and Ad-HIV env priming/Tat and envelope protein boosting regimen elicits enhanced protective efficacy against simian/human immunodeficiency virus SHIV89.6P challenge in rheAntibodies to gp120 and PD-1 expression on virus-specific CD8+ T cells in protection from simian AIDSSequential priming with simian immunodeficiency virus (SIV) DNA vaccines, with or without encoded cytokines, and a replicating adenovirus-SIV recombinant followed by protein boosting does not control a pathogenic SIVmac251 mucosal challengeProtection against mucosal simian immunodeficiency virus SIV(mac251) challenge by using replicating adenovirus-SIV multigene vaccine priming and subunit boosting.Correlation of vaccine-elicited systemic and mucosal nonneutralizing antibody activities with reduced acute viremia following intrarectal simian immunodeficiency virus SIVmac251 challenge of rhesus macaques.Contribution of nonneutralizing vaccine-elicited antibody activities to improved protective efficacy in rhesus macaques immunized with Tat/Env compared with multigenic vaccines.Prospects for oral replicating adenovirus-vectored vaccines.Immune response in rhesus macaques after mixed modality immunisations with DNA, recombinant adenovirus and recombinant gp120 from human immunodeficiency virus type 1.Single-cycle adenovirus vectors in the current vaccine landscape.Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responses against highly conserved viral sequences during simian-human immunodeficiency virus infection.Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development
P2860
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P2860
Boosting of SIV-specific immune responses in rhesus macaques by repeated administration of Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinants.
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Boosting of SIV-specific immun ...... and Ad5hr-SIVgag recombinants.
@ast
Boosting of SIV-specific immun ...... and Ad5hr-SIVgag recombinants.
@en
type
label
Boosting of SIV-specific immun ...... and Ad5hr-SIVgag recombinants.
@ast
Boosting of SIV-specific immun ...... and Ad5hr-SIVgag recombinants.
@en
prefLabel
Boosting of SIV-specific immun ...... and Ad5hr-SIVgag recombinants.
@ast
Boosting of SIV-specific immun ...... and Ad5hr-SIVgag recombinants.
@en
P2093
P1433
P1476
Boosting of SIV-specific immun ...... and Ad5hr-SIVgag recombinants.
@en
P2093
David Venzon
George N Pavlakis
Joel Pinczewski
Kristine Aldrich
L Jean Patterson
Marjorie Robert-Guroff
Nina Malkevitch
Ruth Woodward
P304
P356
10.1016/S0264-410X(03)00266-4
P407
P577
2003-09-01T00:00:00Z