Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development
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Sang Froid in a time of trouble: is a vaccine against HIV possible?Recombinant Yellow Fever Vaccine Virus 17D Expressing Simian Immunodeficiency Virus SIVmac239 Gag Induces SIV-Specific CD8+ T-Cell Responses in Rhesus MacaquesHeterologous Prime-Boost HIV-1 Vaccination Regimens in Pre-Clinical and Clinical TrialsMucosal immunity and protection against HIV/SIV infection: strategies and challenges for vaccine design.Controlling the HIV/AIDS epidemic: current status and global challengesDevelopment of replication-competent viral vectors for HIV vaccine delivery.Construction and immunogenicity of replication-competent adenovirus 5 host range mutant recombinants expressing HIV-1 gp160 of SF162 and TV1 strains.Humoral immunity induced by mucosal and/or systemic SIV-specific vaccine platforms suggests novel combinatorial approaches for enhancing responses.Multiple vaccine-elicited nonneutralizing antienvelope antibody activities contribute to protective efficacy by reducing both acute and chronic viremia following simian/human immunodeficiency virus SHIV89.6P challenge in rhesus macaques.The influence of delivery vectors on HIV vaccine efficacyComparative analysis of SIV-specific cellular immune responses induced by different vaccine platforms in rhesus macaquesEffects of the deletion of early region 4 (E4) open reading frame 1 (orf1), orf1-2, orf1-3 and orf1-4 on virus-host cell interaction, transgene expression, and immunogenicity of replicating adenovirus HIV vaccine vectors.Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges.Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac2Replicating adenovirus-simian immunodeficiency virus (SIV) vectors efficiently prime SIV-specific systemic and mucosal immune responses by targeting myeloid dendritic cells and persisting in rectal macrophages, regardless of immunization route.Beyond Oncolytics: E1B55K-Deleted Adenovirus as a Vaccine Delivery Vector.Correlation of vaccine-elicited systemic and mucosal nonneutralizing antibody activities with reduced acute viremia following intrarectal simian immunodeficiency virus SIVmac251 challenge of rhesus macaques.Rhesus macaque rectal and duodenal tissues exhibit B-cell sub-populations distinct from peripheral blood that continuously secrete antigen-specific IgA in short-term explant cultures.DNA vaccines for targeting bacterial infections.Prime-boost immunization with poxvirus or adenovirus vectors as a strategy to develop a protective vaccine for HIV-1.Therapeutic and prophylactic DNA vaccines for HIV-1.
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Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development
description
article
@en
im September 2008 veröffentlichter wissenschaftlicher Artikel
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wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 2008
@uk
name
Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development
@en
Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development
@nl
type
label
Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development
@en
Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development
@nl
prefLabel
Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development
@en
Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development
@nl
P2860
P1476
Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development
@en
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L Jean Patterson
Marjorie Robert-Guroff
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10.1517/14712598.8.9.1347
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P577
2008-09-01T00:00:00Z