Cognitive decline, neuromotor and behavioural disturbances in a mouse model for fragile-X-associated tremor/ataxia syndrome (FXTAS).
about
The multiple molecular facets of fragile X-associated tremor/ataxia syndromeUnstable mutations in the FMR1 gene and the phenotypesThe unstable repeats--three evolving faces of neurological diseasePremutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.Comprehensive neurocognitive endophenotyping strategies for mouse models of genetic disordersCGG repeat in the FMR1 gene: size mattersImproved methodology for assessment of mRNA levels in blood of patients with FMR1 related disordersMouse models of fragile X-associated tremor ataxia.CNS expression of murine fragile X protein (FMRP) as a function of CGG-repeat size.Evidence for RNA-mediated toxicity in the fragile X-associated tremor/ataxia syndrome.Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile X mental retardation gene 1 premutation carriers with fragile X-associated tremor/ataxia syndrome.Advances in understanding the molecular basis of FXTASTemporal ordering deficits in female CGG KI mice heterozygous for the fragile X premutation.Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndromeFragile X and autism: Intertwined at the molecular level leading to targeted treatments.Cerebral protein synthesis in a knockin mouse model of the fragile X premutation.Activation of mTOR ameliorates fragile X premutation rCGG repeat-mediated neurodegenerationUbiquitin-positive intranuclear inclusions in neuronal and glial cells in a mouse model of the fragile X premutation.Motor deficits on a ladder rung task in male and female adolescent and adult CGG knock-in miceMouse models of the fragile x premutation and the fragile X associated tremor/ataxia syndrome.Abnormal dendrite and spine morphology in primary visual cortex in the CGG knock-in mouse model of the fragile X premutationThe FMR1 gene and fragile X-associated tremor/ataxia syndrome.A mouse model of the fragile X premutation: effects on behavior, dendrite morphology, and regional rates of cerebral protein synthesis.Altered hypothalamus-pituitary-adrenal gland axis regulation in the expanded CGG-repeat mouse model for fragile X-associated tremor/ataxia syndrome.Widespread non-central nervous system organ pathology in fragile X premutation carriers with fragile X-associated tremor/ataxia syndrome and CGG knock-in mice.Elevated Fmr1 mRNA levels and reduced protein expression in a mouse model with an unmethylated Fragile X full mutation.Female CGG knock-in mice modeling the fragile X premutation are impaired on a skilled forelimb reaching taskThe importance of considering all attributes of memory in behavioral endophenotyping of mouse models of genetic disease.Induced expression of expanded CGG RNA causes mitochondrial dysfunction in vivoCGG trinucleotide repeat length modulates neural plasticity and spatiotemporal processing in a mouse model of the fragile X premutation.Neurodegeneration the RNA wayThe fragile X continuum: new advances and perspectives.FMR1: a gene with three faces.Ectopic expression of CGG containing mRNA is neurotoxic in mammals.Molecular pathogenesis of fragile X-associated tremor/ataxia syndromeMurine hippocampal neurons expressing Fmr1 gene premutations show early developmental deficits and late degeneration.Fragile X-associated tremor/ataxia syndrome (FXTAS): pathology and mechanisms.Neurocognitive endophenotypes in CGG KI and Fmr1 KO mouse models of Fragile X-Associated disorders: an analysis of the state of the fieldModifiers and mechanisms of multi-system polyglutamine neurodegenerative disorders: lessons from fly models.RNA-binding proteins involved in RNA localization and their implications in neuronal diseases.
P2860
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P2860
Cognitive decline, neuromotor and behavioural disturbances in a mouse model for fragile-X-associated tremor/ataxia syndrome (FXTAS).
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Cognitive decline, neuromotor ...... remor/ataxia syndrome (FXTAS).
@ast
Cognitive decline, neuromotor ...... remor/ataxia syndrome (FXTAS).
@en
type
label
Cognitive decline, neuromotor ...... remor/ataxia syndrome (FXTAS).
@ast
Cognitive decline, neuromotor ...... remor/ataxia syndrome (FXTAS).
@en
prefLabel
Cognitive decline, neuromotor ...... remor/ataxia syndrome (FXTAS).
@ast
Cognitive decline, neuromotor ...... remor/ataxia syndrome (FXTAS).
@en
P2093
P1476
Cognitive decline, neuromotor ...... tremor/ataxia syndrome (FXTAS)
@en
P2093
Ben A Oostra
Debby Van Dam
Edwin Mientjes
Peter Paul De Deyn
Rob Willemsen
Vanessa Errijgers
P304
P356
10.1016/J.BBR.2005.03.007
P407
P50
P577
2005-07-01T00:00:00Z