LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers.
about
Near IR heptamethine cyanine dye-mediated cancer imagingIsolation and characterization of a digoxin transporter and its rat homologue expressed in the kidneyEffect of SLCO1B3 haplotype on testosterone transport and clinical outcome in caucasian patients with androgen-independent prostatic cancerThe Regulation of Steroid Action by Sulfation and DesulfationRole of Organic Anion-Transporting Polypeptides (OATPs) in Cancer TherapyOATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesPharmacogenomics of chemotherapeutic susceptibility and toxicityRole of solute carriers in response to anticancer drugsInhibition of OATP-1B1 and OATP-1B3 by tyrosine kinase inhibitorsComplete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liverOrganic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugsMolecular characterization of human and rat organic anion transporter OATP-DRole of transmembrane domain 10 for the function of organic anion transporting polypeptide 1B1.Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.Identification, Ki determination and CoMFA analysis of nuclear receptor ligands as competitive inhibitors of OATP1B1-mediated estradiol-17beta-glucuronide transportCloning/characterization of the canine organic anion transporting polypeptide 1b4 (Oatp1b4) and classification of the canine OATP/SLCO membersCyanobacterial cyclopeptides as lead compounds to novel targeted cancer drugsOrganic anion transporting polypeptide 1B3 can form homo- and hetero-oligomersDevelopment of a cell-based high-throughput assay to screen for inhibitors of organic anion transporting polypeptides 1B1 and 1B3.Mechanisms of membrane transport of folates into cells and across epithelia.Developmental pharmacogenetics in pediatric rheumatology: utilizing a new paradigm to effectively treat patients with juvenile idiopathic arthritis with methotrexate.The SLCO (former SLC21) superfamily of transporters.Several conserved positively charged amino acids in OATP1B1 are involved in binding or translocation of different substratesThe intestinal absorption of folates.Genome-wide association studies in pharmacogenomics: successes and lessons.Identification of novel functional organic anion-transporting polypeptide 1B3 polymorphisms and assessment of substrate specificity.Impact of OATP transporters on pharmacokinetics.Molecular cloning and functional characterization of a rainbow trout liver Oatp.Pharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney.Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets.Unique expression features of cancer-type organic anion transporting polypeptide 1B3 mRNA expression in human colon and lung cancers.Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome.PharmGKB summary: methotrexate pathway.Association of CYP2D6*10, OATP1B1 A388G, and OATP1B1 T521C polymorphisms and overall survival of breast cancer patients after tamoxifen therapyIntroduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.Isolation of modulators of the liver-specific organic anion-transporting polypeptides (OATPs) 1B1 and 1B3 from Rollinia emarginata Schlecht (Annonaceae).Resistance to antifolates.Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate dispositionThe expression and function of organic anion transporting polypeptides in normal tissues and in cancerSubstrate- and pH-specific antifolate transport mediated by organic anion-transporting polypeptide 2B1 (OATP2B1-SLCO2B1)
P2860
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P2860
LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
LST-2, a human liver-specific ...... y in gastrointestinal cancers.
@ast
LST-2, a human liver-specific ...... y in gastrointestinal cancers.
@en
type
label
LST-2, a human liver-specific ...... y in gastrointestinal cancers.
@ast
LST-2, a human liver-specific ...... y in gastrointestinal cancers.
@en
prefLabel
LST-2, a human liver-specific ...... y in gastrointestinal cancers.
@ast
LST-2, a human liver-specific ...... y in gastrointestinal cancers.
@en
P2093
P356
P1433
P1476
LST-2, a human liver-specific ...... ty in gastrointestinal cancers
@en
P2093
K Fujiwara
P304
P356
10.1053/GAST.2001.24804
P407
P577
2001-06-01T00:00:00Z