Nucleotide sequences and three-dimensional modelling of the VH and VL domains of two human monoclonal antibodies specific for the D antigen of the human Rh-blood-group system.
about
Rheumatoid factors isolated from patients with autoimmune disorders are derived from germline genes distinct from those encoding the Wa, Po, and Bla cross-reactive idiotypes.Cloning and sequencing of human lambda immunoglobulin genes by the polymerase chain reaction.Defining the genetic origins of three rheumatoid synovium-derived IgG rheumatoid factors.Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody.Sequence analyses of three immunoglobulin G anti-virus antibodies reveal their utilization of autoantibody-related immunoglobulin Vh genes, but not V lambda genes.Nucleotide sequence analysis of rheumatoid factors and polyreactive antibodies derived from patients with rheumatoid arthritis reveals diverse use of VH and VL gene segments and extensive variability in CDR-3.A novel gene product associated with mu chains in immature B cells.Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.The Rh antigen D: partial D antigens and associated low incidence antigens.Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus.Molecular characterization of a human anti-Rh(D) antibody with a DH segment encoded by a germ-line sequence.Human monoclonal antibodies to C, c, E, e and G antigens of the Rh system.Human monoclonal antibodies against blood group antigens preferentially express a VH4-21 variable region gene-associated epitope.Molecular analysis of rheumatoid factors derived from rheumatoid synovium suggests an antigen-driven response in inflamed joints.Novel diagnostic and therapeutic strategies with genetically engineered human antibodies.
P2860
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P2860
Nucleotide sequences and three-dimensional modelling of the VH and VL domains of two human monoclonal antibodies specific for the D antigen of the human Rh-blood-group system.
description
1990 nî lūn-bûn
@nan
1990 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
name
Nucleotide sequences and three ...... e human Rh-blood-group system.
@ast
Nucleotide sequences and three ...... e human Rh-blood-group system.
@en
type
label
Nucleotide sequences and three ...... e human Rh-blood-group system.
@ast
Nucleotide sequences and three ...... e human Rh-blood-group system.
@en
prefLabel
Nucleotide sequences and three ...... e human Rh-blood-group system.
@ast
Nucleotide sequences and three ...... e human Rh-blood-group system.
@en
P2093
P2860
P356
P1433
P1476
Nucleotide sequences and three ...... e human Rh-blood-group system.
@en
P2093
P2860
P304
P356
10.1042/BJ2680135
P407
P577
1990-05-01T00:00:00Z