Modelling the evolution and spread of HIV immune escape mutants
about
Hybrid spreading mechanisms and T cell activation shape the dynamics of HIV-1 infectionRole of HLA Adaptation in HIV EvolutionViral quasispecies evolutionHIV-1 Env C2-V4 diversification in a slow-progressor infant reveals a flat but rugged fitness landscapeThe effect of heterogeneity on invasion in spatial epidemics: from theory to experimental evidence in a model systemEstimating the fitness cost of escape from HLA presentation in HIV-1 protease and reverse transcriptase.Early immune adaptation in HIV-1 revealed by population-level approaches.Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation.Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence.The Effect of Interference on the CD8(+) T Cell Escape Rates in HIV.Structured observations reveal slow HIV-1 CTL escape.Genotypic and functional impact of HIV-1 adaptation to its host population during the North American epidemic.Isolation of a TRAIL antagonist from the serum of HIV-infected patients.The route of HIV escape from immune response targeting multiple sites is determined by the cost-benefit tradeoff of escape mutations.Immuno-epidemiological modeling of HIV-1 predicts high heritability of the set-point virus load, while selection for CTL escape dominates virulence evolutionPopulation-Level Immune-Mediated Adaptation in HIV-1 Polymerase during the North American EpidemicCD8+ clonality is associated with prolonged acute plasma viremia and altered mRNA cytokine profiles during the course of feline immunodeficiency virus infection.Can Horton hear the whos? The importance of scale in mosquito-borne disease.HIV-1 adaptation to NK cell-mediated immune pressure.Optimal viral immune surveillance evasion strategiesModelling the spread of HIV immune escape mutants in a vaccinated population.Cytotoxic T-lymphocyte escape mutations identified by HLA association favor those which escape and revert rapidly.Estimating the impact of antiretroviral treatment on adult mortality trends in South Africa: A mathematical modelling study.Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes.New insights into the evolutionary rate of HIV-1 at the within-host and epidemiological levelsRecombinant GII.P16/GII.4 Sydney 2012 Was the Dominant Norovirus Identified in Australia and New Zealand in 2017Estimating the mutational fitness effects distribution during early HIV infectionGenetic divergence of HIV-1 B subtype in Italy over the years 2003-2016 and impact on CTL escape prevalence
P2860
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P2860
Modelling the evolution and spread of HIV immune escape mutants
description
2010 nî lūn-bûn
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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Modelling the evolution and spread of HIV immune escape mutants
@ast
Modelling the evolution and spread of HIV immune escape mutants
@en
type
label
Modelling the evolution and spread of HIV immune escape mutants
@ast
Modelling the evolution and spread of HIV immune escape mutants
@en
prefLabel
Modelling the evolution and spread of HIV immune escape mutants
@ast
Modelling the evolution and spread of HIV immune escape mutants
@en
P2093
P2860
P1433
P1476
Modelling the evolution and spread of HIV immune escape mutants
@en
P2093
Angela R McLean
Helen R Fryer
Mick G Roberts
Rodney E Phillips
SPARTAC Trial Investigators
P2860
P304
P356
10.1371/JOURNAL.PPAT.1001196
P50
P577
2010-11-18T00:00:00Z