Improvements to the Kunkel mutagenesis protocol for constructing primary and secondary phage-display libraries.
about
A remarkable career in science-Joseph G. GallDirected Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase.Generating conformation-specific synthetic antibodies to trap proteins in selected functional statesRandom mutagenesis of BoNT/E Hc nanobody to construct a secondary phage-display library.Development of a 'mouse and human cross-reactive' affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy.In vivo elimination of parental clones in general and site-directed mutagenesisIncreased Fab thermoresistance via VH-targeted directed evolution.Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step.Molecular and chemical engineering of bacteriophages for potential medical applications.Tandem phage-display for the identification of non-overlapping binding pairs of recombinant affinity reagents.A quantitative PCR-based assay reveals that nucleotide excision repair plays a predominant role in the removal of DNA-protein crosslinks from plasmids transfected into mammalian cells.Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3Generating FN3-Based Affinity Reagents Through Phage DisplayConstruction of Synthetic Phage Displayed Fab Library with Tailored Diversity
P2860
Q28293987-47EBAE29-EF05-4451-B1D4-E6E3F0A2189DQ30009044-A5C584E5-0D4D-4388-93FD-32DB6094DC95Q34528889-F7877F95-B735-4C64-BA05-2AA25C61EE2AQ35157493-3F48AF98-896A-4A06-B306-69DA8C66C3AAQ35158112-B3B1379A-DA97-4FC9-A9CD-3611BACFF65EQ35384515-AC87D48B-0830-4B1A-93CB-FCB0A1B1C331Q35748485-41D33CE4-030C-4BBC-B101-A81620922462Q35799445-4E4042D9-A6A4-4294-814B-DBC324E7B92EQ38232491-A2B4A306-9C9F-41D3-B918-697CC0DCAC2BQ47686932-FA523098-52A3-4CDB-BD88-1F6F4A65E76BQ50056219-5309F210-CEEA-4FA7-90D4-107A50F690EDQ56888637-B7E03B9F-2940-4B95-9405-A8FFD9866628Q56889298-6DBC8D4F-8B68-4FF3-9445-C50D3F5DBE3BQ56889426-B7413EF1-4B27-4C69-84FF-66AE5D1B8F41
P2860
Improvements to the Kunkel mutagenesis protocol for constructing primary and secondary phage-display libraries.
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
Improvements to the Kunkel mut ...... ndary phage-display libraries.
@ast
Improvements to the Kunkel mut ...... ndary phage-display libraries.
@en
type
label
Improvements to the Kunkel mut ...... ndary phage-display libraries.
@ast
Improvements to the Kunkel mut ...... ndary phage-display libraries.
@en
prefLabel
Improvements to the Kunkel mut ...... ndary phage-display libraries.
@ast
Improvements to the Kunkel mut ...... ndary phage-display libraries.
@en
P2093
P2860
P1433
P1476
Improvements to the Kunkel mut ...... ndary phage-display libraries.
@en
P2093
Brian K Kay
Renhua Huang
P2860
P356
10.1016/J.YMETH.2012.08.008
P577
2012-08-30T00:00:00Z