In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library
about
Association of yeast adenylyl cyclase with cyclase-associated protein CAP forms a second Ras-binding site which mediates its Ras-dependent activationSemisynthetic combinatorial antibody libraries: a chemical solution to the diversity problemDNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolutionSelection, affinity maturation, and characterization of a human scFv antibody against CEA proteinIn Vitro Selection of Cancer Cell-Specific Molecular Recognition Elements from Amino Acid LibrariesCoiled-coil interaction of N-terminal 36 residues of cyclase-associated protein with adenylyl cyclase is sufficient for its function in Saccharomyces cerevisiae ras pathway.Construction and characterization of single-chain variable fragment antibody library derived from germline rearranged immunoglobulin variable genesRise and fall of an anti-MUC1 specific antibodyDirected Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase.'In vitro evolution' of ligands for HCV-specific serum antibodies.Erythropoiesis: Splenic Immunoglobulin Variable Region Genes Encoding Red Blood Cell Binding Fab Fragments in Autoimmune Hemolytic Anemia.Human antibodies against spores of the genus Bacillus: a model study for detection of and protection against anthrax and the bioterrorist threat.A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies.Improving antibody affinity by mimicking somatic hypermutation in vitro.In vitro antibody evolution targeting germline hot spots to increase activity of an anti-CD22 immunotoxin.Recombinant single-chain variable fragment antibodies directed against Clostridium difficile toxin B produced by use of an optimized phage display systemHuman recombinant antimannan immunoglobulin G1 antibody confers resistance to hematogenously disseminated candidiasis in mice.An improved helper phage system for efficient isolation of specific antibody molecules in phage displayQuantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies.By-passing selection: direct screening for antibody-antigen interactions using protein arraysSelective recognition of peptide sequences by glutathione transferases: a possible mechanism for modulation of cellular stress-induced signaling pathways.A binary plasmid system for shuffling combinatorial antibody libraries.In vitro selection of fibronectin gain-of-function mutationsImprovements to the Kunkel mutagenesis protocol for constructing primary and secondary phage-display libraries.Single-chain variable fragment antibodies against the neural adhesion molecule CHL1 (close homolog of L1) enhance neurite outgrowth.A general method for greatly improving the affinity of antibodies by using combinatorial librariesHigh affinity mouse-human chimeric Fab against hepatitis B surface antigen.Use of molecular modeling and site-directed mutagenesis to define the structural basis for the immune response to carbohydrate xenoantigens.Design of synthetic antibody libraries.Construction of a large naïve human phage-displayed Fab library through one-step cloning.An improved phage-display panning method to produce an HM-1 killer toxin anti-idiotypic antibody.RNA recognition by a human antibody against brain cytoplasmic 200 RNAAffinity-matured anti-glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas.A novel β-loop scaffold of phage-displayed peptides for highly specific affinities.Ribosome display of combinatorial antibody libraries derived from mice immunized with heat-killed Xylella fastidiosa and the selection of MopB-specific single-chain antibodies.Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene librariesAn efficient method for variable region assembly in the construction of scFv phage display libraries using independent strand amplification.Specific targeting of hepatitis C virus core protein by an intracellular single-chain antibody of human origin.A hierarchical approach to protein molecular evolutionPhage antibody display libraries: a powerful antibody discovery platform for immunotherapy.
P2860
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P2860
In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library
description
1992 nî lūn-bûn
@nan
1992 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
In vitro selection and affinit ...... atorial immunoglobulin library
@ast
In vitro selection and affinit ...... atorial immunoglobulin library
@en
type
label
In vitro selection and affinit ...... atorial immunoglobulin library
@ast
In vitro selection and affinit ...... atorial immunoglobulin library
@en
prefLabel
In vitro selection and affinit ...... atorial immunoglobulin library
@ast
In vitro selection and affinit ...... atorial immunoglobulin library
@en
P2093
P2860
P356
P1476
In vitro selection and affinit ...... atorial immunoglobulin library
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.8.3576
P407
P577
1992-04-01T00:00:00Z