A specific interaction between muskelin and the cyclin-dependent kinase 5 activator p39 promotes peripheral localization of muskelin.
about
Structure of mouse muskelin discoidin domain and biochemical characterization of its self-associationNeuronal expression of muskelin in the rodent central nervous system.The CDK5 activator, p39, binds specifically to myosin essential light chain.Cdk5 activity in the brain - multiple paths of regulation.Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expressionThe Cdk5 activator P39 specifically links muskelin to myosin II and regulates stress fiber formation and actin organization in lens.Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons.The Cdk5 inhibitor olomoucine promotes corneal debridement wound closure in vivo.The role of the lens actin cytoskeleton in fiber cell elongation and differentiation.Novel role of the muskelin-RanBP9 complex as a nucleocytoplasmic mediator of cell morphology regulation.Structural basis for the different stability and activity between the Cdk5 complexes with p35 and p39 activators.Cdk5-dependent regulation of Rho activity, cytoskeletal contraction, and epithelial cell migration via suppression of Src and p190RhoGAPAlternative splicing of T-box transcription factor genes.Cdk5--p39 is a labile complex with the similar substrate specificity to Cdk5--p35.Decreased expression of p39 is associated with a poor prognosis in human hepatocellular carcinoma.MKLN1 splicing defect in dogs with lethal acrodermatitis.
P2860
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P2860
A specific interaction between muskelin and the cyclin-dependent kinase 5 activator p39 promotes peripheral localization of muskelin.
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A specific interaction between ...... eral localization of muskelin.
@ast
A specific interaction between ...... eral localization of muskelin.
@en
type
label
A specific interaction between ...... eral localization of muskelin.
@ast
A specific interaction between ...... eral localization of muskelin.
@en
prefLabel
A specific interaction between ...... eral localization of muskelin.
@ast
A specific interaction between ...... eral localization of muskelin.
@en
P2093
P2860
P356
P1476
A specific interaction between ...... eral localization of muskelin.
@en
P2093
Brajendra K Tripathi
Chun Y Gao
Dolena R Ledee
Peggy S Zelenka
Ranjana Seth
Robert N Fariss
P2860
P304
21376-21383
P356
10.1074/JBC.M501215200
P407
P577
2005-03-28T00:00:00Z