Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism.
about
Targeting multidrug resistance in cancerDrug binding in human P-glycoprotein causes conformational changes in both nucleotide-binding domains.Identification of inhibitors of vacuolar proton-translocating ATPase pumps in yeast by high-throughput screening flow cytometry.Mechanism Underlying the Reversal of Drug Resistance in P-Glycoprotein-Expressing Leukemia Cells by Pinoresinol and the Study of a DerivativeExploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer.Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation.Inhibition of multidrug resistance-linked P-glycoprotein (ABCB1) function by 5'-fluorosulfonylbenzoyl 5'-adenosine: evidence for an ATP analogue that interacts with both drug-substrate-and nucleotide-binding sitesIncreased permeability-glycoprotein inhibition at the human blood-brain barrier can be safely achieved by performing PET during peak plasma concentrations of tariquidar.An update on antifungal targets and mechanisms of resistance in Candida albicans.Recent advances of cocktail chemotherapy by combination drug delivery systems.The cytotoxic mechanisms of disulfiram and copper(ii) in cancer cells.Disulfiram deregulates HIF-α subunits and blunts tumor adaptation to hypoxia in hepatoma cellsThe P-glycoprotein multidrug transporter.Novel naphthalimide-benzoic acid conjugates as potential apoptosis-inducing agents: design, synthesis, and biological activity.Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth.Multidrug resistance protein 4 (ABCC4)-mediated ATP hydrolysis: effect of transport substrates and characterization of the post-hydrolysis transition state.Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein.Cross-linking of human multidrug resistance P-glycoprotein by the substrate, tris-(2-maleimidoethyl)amine, is altered by ATP hydrolysis. Evidence for rotation of a transmembrane helix.Determining the dimensions of the drug-binding domain of human P-glycoprotein using thiol cross-linking compounds as molecular rulers.The "LSGGQ" motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing walker A sequence.How could a drug used to treat alcoholism also be effective against glioblastoma?Disulfiram combined with copper inhibits metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma through the NF-κB and TGF-β pathways.pH-triggered surface charge-switchable polymer micelles for the co-delivery of paclitaxel/disulfiram and overcoming multidrug resistance in cancer.The Design and Development of Potent Small Molecules as Anticancer Agents Targeting EGFR TK and Tubulin Polymerization.Repurposing disulfiram for cancer therapy via targeted nanotechnology through enhanced tumor mass penetration and disassembly.Sulfonamide derivatives with protease inhibitory action as anticancer, anti-inflammatory and antiviral agentsAgents that target cysteine residues of biomolecules and their therapeutic potential
P2860
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P2860
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism.
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism.
@ast
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism.
@en
type
label
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism.
@ast
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism.
@en
prefLabel
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism.
@ast
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism.
@en
P356
P1476
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism.
@en
P2093
P304
P356
10.1093/JNCI/92.11.898
P407
P577
2000-06-01T00:00:00Z