Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein.
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A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathwaysP53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance.Statin therapy and autoimmune disease: from protein prenylation to immunomodulationA mechanistic, model-based approach to safety assessment in clinical development3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy.Antiarrhythmic effects of simvastatin in canine pulmonary vein sleeve preparationsIntercellular adhesion molecule-1 in the heart.HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7.Simvastatin prevents and reverses depigmentation in a mouse model of vitiligoPluripotential mechanisms of cardioprotection with HMG-CoA reductase inhibitor therapy.ATP-dependent potassium channels are implicated in simvastatin pretreatment-induced inhibition of apoptotic cell death after renal ischemia/reperfusion injury.Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption.Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study.Statins as antiinflammatory and immunomodulatory agents: a future in rheumatologic therapy?Statins and the vascular endothelial inflammatory responseSimvastatin improves the homing of BMSCs via the PI3K/AKT/miR-9 pathway.Immunomodulation by statins: mechanisms and potential impact on autoimmune diseases.Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer.The Helicobacter cinaedi antigen CAIP participates in atherosclerotic inflammation by promoting the differentiation of macrophages in foam cellsSimvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth.Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy.Effects of statins on microglia.Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome.The rapid lipopolysaccharide-induced release of matrix metalloproteinases 9 is suppressed by simvastatin.The ocular toxicity and pharmacokinetics of simvastatin following intravitreal injection in mice.Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells.Effects of lipid-lowering drugs on reverse cholesterol transport gene expressions in peripheral blood mononuclear and HepG2 cells.Statins and modulation of oxidative stress.Statins prevent endothelial cell activation induced by antiphospholipid (anti-beta2-glycoprotein I) antibodies: effect on the proadhesive and proinflammatory phenotype.Effects of statins on adhesion molecule expression in endothelial cells.Low level of inflammatory marker in hyperhomocysteinemic patients on statin therapy.Statins suppress glucose-induced plasminogen activator inhibitor-1 expression by regulating RhoA and nuclear factor-κB activities in cardiac microvascular endothelial cells.Hydroxychloroquine decreases human MSC-derived osteoblast differentiation and mineralization in vitro.Statins decrease leptin expression in human white adipocytes.Genetic and Pharmacological Modulation of Akt1 for Improving Ovarian Graft Revascularization in a Mouse Model.Modulation of adhesion molecule expression on endothelial cells: to be or not to be?
P2860
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P2860
Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein.
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Simvastatin modulates cytokine ...... nt of an inhibitory G protein.
@ast
Simvastatin modulates cytokine ...... nt of an inhibitory G protein.
@en
type
label
Simvastatin modulates cytokine ...... nt of an inhibitory G protein.
@ast
Simvastatin modulates cytokine ...... nt of an inhibitory G protein.
@en
prefLabel
Simvastatin modulates cytokine ...... nt of an inhibitory G protein.
@ast
Simvastatin modulates cytokine ...... nt of an inhibitory G protein.
@en
P2093
P1476
Simvastatin modulates cytokine ...... nt of an inhibitory G protein.
@en
P2093
P304
P356
10.4049/JIMMUNOL.165.5.2712
P407
P577
2000-09-01T00:00:00Z