3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy.

3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy.

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http://www.wikidata.org/entity/Q34032435

Q34032435

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Potential Renoprotective Agents through Inhibiting CTGF/CCN2 in Diabetic Nephropathy Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis Rosuvastatin protects against podocyte apoptosis in vitro Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis Effects of Dangguibuxue decoction on rat glomerular mesangial cells cultured under high glucose conditions Statins in the treatment of polycystic ovary syndrome.Modulation of renal-specific oxidoreductase/myo-inositol oxygenase by high-glucose ambience.Simvastatin Enhances the Effects of Radiotherapy and Cetuximab on a Cell Line (FaDu) Derived from a Squamous Cell Carcinoma of Head and Neck Fluorofenidone offers improved renoprotection at early interventions during the course of diabetic nephropathy in db/db mice via multiple pathways Statins and prostate cancer risk: a case-control study.MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy.Effects of statins on the risk of hepatocellular carcinoma Epac1-mediated, high glucose-induced renal proximal tubular cells hypertrophy via the Akt/p21 pathway Acute tubular injury causes dysregulation of cellular cholesterol transport proteins.Cancer risk in HBV patients with statin and metformin use: a population-based cohort study.Statin-Based Palliative Therapy for Hepatocellular Carcinoma Evidence for statin therapy in polycystic ovary syndrome.Treatment of relapsing paralysis in experimental encephalomyelitis by targeting Th1 cells through atorvastatin Drug insight: Immunomodulatory effects of statins--potential benefits for renal patients?Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells.Effects of simvastatin on retinoic acid system in primary human endometrial stromal cells and in a chimeric model of human endometriosis.myo-Inositol Oxygenase Overexpression Accentuates Generation of Reactive Oxygen Species and Exacerbates Cellular Injury following High Glucose Ambience: A NEW MECHANISM RELEVANT TO THE PATHOGENESIS OF DIABETIC NEPHROPATHY Insights into the Mechanisms Involved in the Expression and Regulation of Extracellular Matrix Proteins in Diabetic Nephropathy.Corosolic acid inhibits the proliferation of glomerular mesangial cells and protects against diabetic renal damage A glimpse of various pathogenetic mechanisms of diabetic nephropathy.Rho-kinase mediates hyperglycemia-induced plasminogen activator inhibitor-1 expression in vascular endothelial cells.Statins are associated with a reduced risk of hepatocellular carcinoma in a large cohort of patients with diabetes.Statins are Associated With a Reduced Risk of Brain Cancer: A Population-Based Case-Control Study.Statins improve outcomes of nonsurgical curative treatments in hepatocellular carcinoma patients Simvastatin protects against the development of endometriosis in a nude mouse model Podocytes: the Weakest Link in Diabetic Kidney Disease?Role of isoprenylation in simvastatin-induced inhibition of ovarian theca-interstitial growth in the rat.New insights into molecular mechanisms of diabetic kidney disease.Statins dose-dependently exert a chemopreventive effect against lung cancer in COPD patients: a population-based cohort study.Statins dose-dependently exert a significant chemopreventive effect on colon cancer in patients with chronic obstructive pulmonary disease: A population-based cohort study.Pharmacological approaches to the treatment of oxidative stress-induced cardiovascular dysfunctions.Rho kinase inhibition in diabetic kidney disease.Pleiotropic effects of statins: new therapeutic targets in drug design.Research review on the pharmacological effects of astragaloside IV.MiR-135a promotes renal fibrosis in diabetic nephropathy by regulating TRPC1.

P2860

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P2860

3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy.

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