Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping.
about
Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetesNonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene.Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.Transgenic rescue implicates beta2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) miceDistinct genetic control of autoimmune neuropathy and diabetes in the non-obese diabetic background.The genetics of complex autoimmune diseases: non-MHC susceptibility genes.A cluster of coregulated genes determines TGF-beta-induced regulatory T-cell (Treg) dysfunction in NOD miceENU large-scale mutagenesis and quantitative trait linkage (QTL) analysis in mice: novel technologies for searching polygenetic determinants of craniofacial abnormalities.A T cell extrinsic mechanism by which IL-2 dampens Th17 differentiation.The same genomic region conditions clonal deletion and clonal deviation to the CD8alphaalpha and regulatory T cell lineages in NOD versus C57BL/6 mice.Breakdown in peripheral tolerance in type 1 diabetes in mice and humansMouse models of type 1 and type 2 diabetes derived from the same closed colony: genetic susceptibility shared between two types of diabetes.Molecular genetic analysis of two loci (Ity2 and Ity3) involved in the host response to infection with Salmonella typhimurium using congenic mice and expression profilingUtility of murine models for the study of spontaneous autoimmune type 1 diabetes.Modifier loci condition autoimmunity provoked by Aire deficiency.The gene for human IL-21 and genetic susceptibility to type 1 diabetes in the Japanese.Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes.Dissecting genetic control of autoimmunity in NOD congenic mice.NKG2D-RAE-1 receptor-ligand variation does not account for the NK cell defect in nonobese diabetic mice.Tissue- and age-specific changes in gene expression during disease induction and progression in NOD miceCutting edge: the Idd3 genetic interval determines regulatory T cell function through CD11b+CD11c- APC.Reduced IL-2 expression in NOD mice leads to a temporal increase in CD62Llo FoxP3+ CD4+ T cells with limited suppressor activity.Loss of parity between IL-2 and IL-21 in the NOD Idd3 locusThe Spontaneous Autoimmune Neuromyopathy in ICOSL-/- NOD Mice Is CD4+ T-Cell and Interferon-γ DependentMouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease.Type 1 diabetes: etiology, immunology, and therapeutic strategies.Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 familyGenetic analysis of type 1 diabetes: embryonic stem cells as new tools to unlock biological mechanisms in type 1 diabetes.Immune Regulation in T1D and T2D: Prospective Role of Foxp3+ Treg Cells in Disease Pathogenesis and Treatment.Advances in our understanding of the pathophysiology of Type 1 diabetes: lessons from the NOD mouse.Expression of IL-2 in β cells by AAV8 gene transfer in pre-diabetic NOD mice prevents diabetes through activation of FoxP3-positive regulatory T cells.Promoting Immune Regulation in Type 1 Diabetes Using Low-Dose Interleukin-2.IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease.Genome-wide microarray expression analysis of CD4+ T Cells from nonobese diabetic congenic mice identifies Cd55 (Daf1) and Acadl as candidate genes for type 1 diabetes.Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetesGenetic dissection of quantitative trait loci specifying sedative/hypnotic sensitivity to ethanol: mapping with interval-specific congenic recombinant lines.The Role of NOD Mice in Type 1 Diabetes Research: Lessons from the Past and Recommendations for the Future.Identification of QTLs that modify peripheral neuropathy in NOD.H2b-Pdcd1-/- mice.Lrmp and Bcat1 are candidates for the type I diabetes susceptibility locus Idd6.
P2860
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P2860
Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping.
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Congenic mapping of the type 1 ...... tral DNA by haplotype mapping.
@ast
Congenic mapping of the type 1 ...... tral DNA by haplotype mapping.
@en
type
label
Congenic mapping of the type 1 ...... tral DNA by haplotype mapping.
@ast
Congenic mapping of the type 1 ...... tral DNA by haplotype mapping.
@en
prefLabel
Congenic mapping of the type 1 ...... tral DNA by haplotype mapping.
@ast
Congenic mapping of the type 1 ...... tral DNA by haplotype mapping.
@en
P2093
P2860
P356
P1433
P1476
Congenic mapping of the type 1 ...... tral DNA by haplotype mapping.
@en
P2093
F Argentina
L B Peterson
L S Wicker
M B Wilusz
N Armitage
P2860
P304
P356
10.1101/GR.10.4.446
P577
2000-04-01T00:00:00Z